Figure 1

From: Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection

Figure 1

Impaired motor coordination in group A β-hemolytic streptococcus (GABHS) donor mice. Motor coordination of GABHS and phosphate-buffered saline (PBS) donor mice was assessed using an accelerating rotarod test. The length of time the mouse was able to remain on the rod as it accelerated to 20 r.p.m. (a) and the speed at which mice fell off the accelerating rod (b) were measured. GABHS donor mice remained on the rotating rod for shorter intervals, and fell off the rotating rod at slower rotation speeds than PBS donor mice (Fisher's protected least-significant difference (PLSD); *P<0.05). Error bars indicate s.e.m.