Table 1 Dose classifications for selective-serotonin reuptake inhibitors

From: Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder

Medication Minimum (mg) Maximum (mg) Low (mg) Medium (mg) High (mg)
Fluoxetine 20 80 20–30 40–50 60–80
Sertraline 50 200 50–75 100–175 200
Paroxetine 20 60 20–30 40–50 60
Fluvoxamine 150 300 50–150 200–250 300–350
Citalopram 20 60–80 20–30 40–50 60–80
Escitralopram 10 40 10–15 20–25 30–40
  1. These dose categories were defined a priori and were calculated based on fluoxetine equivalents of SSRIs used in previous meta-analytic studies of antidepressants and according to the American Psychiatric Association dose recommendations for individual SSRIs in Obsessive-Compulsive Disorder.9, 11