Table 1 Summary of published cases of deciduoid mesothelioma

From: Deciduoid mesothelioma: report of 21 cases with review of the literature

Author(s) Sex/age Asbestos exposure Location Type of specimen Histology Treatment Follow-up (months)
Talerman et al2 F/13 No Peritoneum Peritoneal biopsies Undifferentiated polygonal cells arranged in a sheet-like pattern. High mitotic activity present, including atypical forms Chemotherapy DOD (8)
Nacimento et al1 F/23 No Peritoneum Peritoneal biopsies Deciduoid INA DOD (4)
  F/24 No Peritoneum Peritoneal biopsies Deciduoid INA INA
Orosz et al3 F/15 No Peritoneum Peritoneal biopsy Large polygonal or ovoid cells arranged in solid sheets or trabeculae. Binucleated cells present. Ten to 15 mitoses per 10 HPF, including atypical Chemotherapy + radiotherapy DOD (11)
Shanks et al4 M/59 No Paratesticular, spermatic cord Orchiectomy, autopsy Deciduoid with occasional tubulopapillary or acinar areas Orchiectomy + chemotherapy DOD (4)
  F/53 Yes Peritoneum Peritoneal biopsies Deciduoid Symptomatic DOD (9)
  M/65 Yes Peritoneum Biopsy + autopsy Deciduoid Tumor resection DOD (4)
  M/55 Yes Peritoneum Tumor resection Deciduoid with tubular and sarcomatoid areas. Multi-nucleated cells and mitoses, including atypical Tumor debulking AWD (60)
  F/55 No Peritoneum Peritoneal biopsies Predominantly tubulopapillary with focal sarcomatoid areas and scattered small groups of deciduoid cells Hysterectomy with bilateral salpingo-ooforectomy DOD (4)
  M/52 Yes Pleura Pleural biopsies Deciduoid with tubulopapillary areas Symptomatic AWD (8)
Ordóñez5 F/46 No Pleura Pneumonectomy Large polygonal or ovoid cells arranged in sheets or trabeculae. Three to five mitoses per 10 HPF Pneumonectomy DOD (6)
  M/64 Yes Pleura Pneumonectomy Sheets of large cells with abundant dense cytoplasm. Two to four mitoses per 10 HPF Chemotherapy + pneumonectomy DOD (8)
  M/60 No Pleura Pneumonectomy Solid sheets of large cells with dense eosinophilic cytoplasm and deciduoid features. Mitotic figures were not uncommon Pneumonectomy + radiation DOD (5)
  M/78 Yes Pleura Pleural fluid Large polygonal cells with abundant eosinophilic cytoplasm INA INA
Gloeckner-Hofmann et al6 F/40 No Pleura Pleural biopsy + tumor resection Deciduoid Chemotherapy DOD
Puttagunta et al7 M/41 No Pleura Pleural biopsy Deciduoid with rhabdoid change Radiotherapy DOD (21)
Desai et al8 F/53 INA Peritoneum Tumor resection Giant cells with abundant eosinophilic cytoplasm and sharp borders. Nuclear pleomorphism with hyperchromasia and prominent nucleoli Debulking + hysterectomy with bilateral salpingo-oophorectomy INA
Gillespie et al9 F/50 No Peritoneum Peritoneal fluid Deciduoid cells, some binucleated or multi-nucleated. An occasional mitosis was seen Chemotherapy AWD (12)
Henley et al10 F/30 No Pleura INA Deciduoid with vacuolated Clear areas. Three mitoses per 10 HPF Surgical resection + chemotherapy AWD (5)
Monaghan and Al-Nafussi11 M/66 Yes Pleura Pleural biopsies Large round, oval, and polygonal cells with abundant eosinophilic cytoplasm. Focal cytoplasmic vacuolization and rare mitoses INA INA
Okonkwo et al12 F/30 No Peritoneum Tumor resection Deciduoid. One to three mitoses per 10 HPF Surgical resection NED (20)
Reis-Filho et al13 F/71 No Pericardium FNA biopsy, autopsy Deciduoid with tubulopapillary areas. Two mitoses per 10 HPF Symptomatic DODa (48 h)
Serio et al14 F/23b No Pleura Pleural biopsy Deciduoid with focal tubulopapillary areas. Two mitoses per 10 HPF Symptomatic DOD (39)
  M/73 Yes Pleura Pleural biopsy Deciduoid with focal tubulopapillary areas. Two mitoses per 10 HPF Chemotherapy DOD (17)
Shia et al15 F/69 INA Pleura Pleurectomy specimen Deciduoid Lobectomy + pleurectomy DOD (17)
  F/51 INA Peritoneum Tumor resection Deciduoid + tubulopapillary (<25%). Some deciduoid cells had pale or clear cytoplasm Tumor debulking DOD (1)
  F/71 No Pleura Decortication Deciduoid Decortication DOD (4)
  M/65 Yes Pleura Pneumonectomy Deciduoid Pneumonectomy + radiation NED (12)
  M/56 Yes Peritoneum Resected specimen Deciduoid + tubulopapillary (<5%) Tumor debulking + chemotherapy DOD (4)
Chung et al16 F/47 No Peritoneum Resected tumor Deciduoid Tumor debulking + chemotherapy AWD (1)
Asioli et al17 M/62 No Pleura, predominantly intrapulmonary localized Lobectomy Deciduoid Lt. upper lobectomy AWD (20)
Maeda et al18 F/24c No Peritoneum localized Resected tumor Deciduoid. Intranuclear inclusions, some cells were multinucleated and some had foamy cytoplasm. Two to three mitoses per 10 HPF Resection NED (32)
Mishra and Shet19 M/75 No Paratesticular, tunica vaginalis Orchiectomy Predominantly composed of clear cells with focal deciduoid and rhabdoid areas. Small areas of tubulopapillary pattern present. Mitoses present Orchiectomy INA
Kimura et al20 M/70 No Peritoneum Peritoneal biopsy, autopsy Deciduoid with irregular nuclei and some multi-nucleated cells. Prominent mucinous stroma INA DOD (12)
Mourra et al21 F/41d No Peritoneum Tumor resection Deciduoid with pleomorphic nuclei and rare mitoses Tumor debulking DOD (14)
Scattone et al22 F/23 Yes Pleura INA Deciduoid Palliative DOD (39)
  M/73 Yes Pleura INA Deciduoid Chemotherapy DOD (43)
  M/71 Yes Pleura INA Deciduoid Chemotherapy DOD (38)
  F/32 Yes Pleura INA Deciduoid Palliative DOD (24)
  F/52 Yes Pleura INA Deciduoid Chemotherapy DOD (24)
  M/74 Yes Pleura INA Deciduoid Chemotherapy DOD (12)
Tsai et al23 M/13 No Pleura Pleural biopsy Deciduoid with binucleated and multinucleated cells Chemotherapy + pneumonectomy + chemotherapy AWD (24)
Ustun et al24 F/59 No Peritoneum FNA, tumor resection Deciduoid with occasional binucleated and multinucleated cells. Pseudonuclear inclusions and a few mitoses were seen Resections NED (3)
  1. Abbreviations: AWD, alive with disease; DOD, died of disease; FNA, fine needle aspiration; INA, information not available; NED, no evidence of disease.
  2. aPatient died 48 h after diagnosis, but had symptoms related to the disease for 8 months.
  3. bFamily history of mesothelioma.
  4. cPatient was pregnant.
  5. dTumor presented 6 months after caesarean section and was initially misinterpreted as pseudotumoral deciduosis.