Table 1: GPC-3 staining results in benign and malignant hepatocellular lesions

From: Utility and limitations of glypican-3 expression for the diagnosis of hepatocellular carcinoma at both ends of the differentiation spectrum

Liver lesionsGPC-3 staininga
 Total positiveDiffuse positive
Benign hepatocellular lesions
 Cirrhotic nodules (n=35)4 (11)0 (0)
 Macroregenerative nodule (n=10)0 (0)0 (0)
 Hepatic adenoma (n=8)0 (0)0 (0)
   
Borderline and malignant lesions
 High-grade dysplastic nodule (n=7)3 (43)0 (0)
 Extremely well-differentiated HCC (n=10)5 (50)2 (20)
 HCC, well differentiated (n=16)b9 (56)5 (31)
 HCC, moderately differentiated (n=18)15 (83)10 (56)
 HCC, poorly differentiated (n=24)22 (89)20 (83)
 Fibrolamellar HCC (n=11)7 (64)4 (36)
  1. HCC, hepatocellular carcinoma.
  2. aFigures in parenthesis reflect percentages.
  3. bIncludes extremely well-differentiated HCC.