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We thank the laboratory members, past and present, for their contributions to this work and acknowledge the funding from the Lady Tata Foundation (BPM) and from the Gabrielle’s Angel Foundation and American Cancer Society (PE). The symposium and publication of this supplement were sponsored by the Division of Hematology/Oncology at the Warren Alpert Medical School of Brown University and NIH Center of Biomedical Research Excellence (COBRE) for Stem Cells Biology at Rhode Island Hospital.
PE owns stock in Amgen and has received grant support from the National Institutes of Health (NHLBI and OD), American Cancer Society and Alex’s Lemonade Stand Foundation. BPM has received funding from the Lady Tata Memorial Trust and declares no conflict of interest.
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Mishra, B., Ernst, P. Deconvoluting MLL1-dependent pathways in hematopoiesis and leukemogenesis. Leukemia Suppl 3, S9–S10 (2014). https://doi.org/10.1038/leusup.2014.5
- Mixed Lineage Leukemia gene
- SET domain
- histone H4 lysine 16 acetylation
- HSC self-renewal
- HSC quiescence