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Chronic lymphocytic leukemia: treatment of relapse

Abstract

Despite significant advances in the frontline treatment of chronic lymphocytic leukemia (CLL), patients eventually experience disease progression. Treatment selection of relapsed disease depends upon a variety of factors, including patient age, performance status, duration of response to initial therapy, type of prior therapy, disease-related manifestations and genetic abnormalities within the CLL cells. This presentation offers synthetic overview of the options in this field.

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Correspondence to M Montillo.

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Competing interests

MM received lecture fees from the Genzyme Corporation, GlaxoSmithKline plc and F. Hoffmann-La Roche Ltd, and grant research support from GlaxoSmithKline plc and Hospira Inc.

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This article was published as part of a supplement that was supported by Novartis, MSD Italia, Roche, Celgene, GlaxoSmithKline, Sanofi, Gilead, Adienne, Italfarmaco, Pierre Fabre Pharmaceuticals with an unrestricted educational contribution to AREO-Associazione Ricerche Emato-Oncologiche (Genoa) and AMS—Associazione Malattie del Sangue (Milan) for the purpose of advancing research in acute and chronic leukemia.

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Montillo, M. Chronic lymphocytic leukemia: treatment of relapse. Leukemia Suppl 1 (Suppl 2), S31–S32 (2012). https://doi.org/10.1038/leusup.2012.18

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