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Discovery and functional characterization of a germline, CSF2RB-activating mutation in leukemia

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Acknowledgements

We thank Dr Caroline Enns and Dr William Skach, for guidance on the non-reducing PAGE experiments. We also thank David K. Edwards V (NSF GRFP DGE-1448072) and Marilynn Chow (Knight Cancer Institute) for critical review of the manuscript. This work was funded by a Howard Hughes Medical Institute Investigator award and NIH/NCI MERIT award (R37CA065823) to BJD, and NIH/NCI R00 award (5R00CA151670-04) to AA. KWS was supported by a T32 program training grant (5T32GM071338-08), Knight Cancer Institute stipend award and the Allan Price memorial ARCS scholar award. BJD and JT are also supported by Leukemia Lymphoma Society (LLS) Beat AML program. JPPM was supported by KiKa foundation grants (2010-082, 2013-123) and the Dutch Cancer society (EMCR-KWF-20110-4691).

Author contributions

KWS designed and performed research, interpreted the data and wrote the manuscript. CT and AA designed the research and edited the manuscript. JPPM supplied essential samples, provided critical feedback and reviewed the manuscript. BJD and JWT provided critical feedback and reviewed the manuscript.

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Correspondence to A Agarwal.

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JWT receives research support from Incyte. The remaining authors declare no conflict of interest.

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Watanabe-Smith, K., Tognon, C., Tyner, J. et al. Discovery and functional characterization of a germline, CSF2RB-activating mutation in leukemia. Leukemia 30, 1950–1953 (2016). https://doi.org/10.1038/leu.2016.95

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