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Diagnosis and relapse: cytogenetically normal acute myelogenous leukemia without FLT3-ITD or MLL-PTD

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Acknowledgements

This work was funded by the Singapore Ministry of Health’s National Medical Research Council (NMRC) under its Singapore Translational Research (STaR) Investigator Award to HPK, the National Research Foundation Singapore and the Singapore Ministry of Education under its Research Centers of Excellence initiative. This study is partially supported by a generous donation from the Melamed family, Eleanor and Glenn Padnick Discovery Fund in Cellular Therapy, and Mr Reuben Yeroushalmi.

Author contributions

WC, Q-YS and L-WD designed the study, performed the experiments, analyzed the data and wrote the manuscript. AM, LL, KTT and HY performed bioinformatics and data analysis. ST, SLL, ADSMV, JX, NJ and KB performed the experiments. MG, CS, ML, VM, NH, SG and SO contributed reagents and assisted with data analysis. SW, TI, L-YS, TA and TH coordinated collection and processing of clinical samples. HPK conceived the project, helped design experiments, analyzed the data and helped to write the manuscript.

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Correspondence to W Chien.

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Competing interests

TH is employed by and partly owns the MLL Munich Leukemia Laboratory. TA is employed by the MLL Munich Leukemia Laboratory. The remaining authors declare no conflict of interest.

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Supplementary Information accompanies this paper on the Leukemia website

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Chien, W., Sun, QY., Ding, LW. et al. Diagnosis and relapse: cytogenetically normal acute myelogenous leukemia without FLT3-ITD or MLL-PTD. Leukemia 31, 762–766 (2017). https://doi.org/10.1038/leu.2016.343

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