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Trisomy 12 CLLs progress through NOTCH1 mutations

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Acknowledgements

The research was supported by the ACS Research Scholar Grant (YP), gift from Swan family (YP), NIH RO1-CA151319 (CMC, PO1-CA81534 of the CLL Research Consortium (lZR, TJK, CMC) and AIL-sezione di Ferrara (lR). We thank Nyla A Heerema (The Ohio State University), Paola Dal Cin, Brigham & Women’s Hospital), Marie L Dell’ Aquila (Moores Cancer Center) Ayala Aviram (North Shore Hospital) and Daniel Van Dyke (Mayo Clinic) for cytogenetic analysis of CLL samples.

Author contributions

YP and CMC designed research; LZR, TJK, SL and MJK provided patient samples and clinical data; VB, AB, YP, AP, HA, LC and LR performed research and analyzed data; and YP, VB and CMC wrote the paper. All authors critically reviewed and edited the paper.

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Correspondence to Y Pekarsky or C M Croce.

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Supplementary Information accompanies the paper on the Leukemia website

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Balatti, V., Lerner, S., Rizzotto, L. et al. Trisomy 12 CLLs progress through NOTCH1 mutations. Leukemia 27, 740–743 (2013). https://doi.org/10.1038/leu.2012.239

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