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BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes
Molecular Cancer Open Access 05 August 2023
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Acknowledgements
BF was supported by an investigator grant from the Associazione Italiana Ricerca sul Cancro and ET was supported by a fellowship (2008/14) from the European Hematology Association. We thank Roberta Pacini and Gianluca Schiavoni for their technical assistance.
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BF and ET applied for a patent on the clinical use of the BRAF V600E mutant in HCL. The remaining authors declare no conflict of interest.
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Kitagawa, Y., Brahmachary, M., Tiacci, E. et al. A microRNA signature specific for hairy cell leukemia and associated with modulation of the MAPK–JNK pathways. Leukemia 26, 2564–2567 (2012). https://doi.org/10.1038/leu.2012.149
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DOI: https://doi.org/10.1038/leu.2012.149