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Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro

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This work was supported by grants from the Norwegian Cancer Society, the Norwegian Research Council, the Swedish Research Council (529-2004-6512 and 521-2006-5103), the Swedish federal government under the LUA/ALF agreement, the Sahlgrenska University Hospital Foundation and the agreement concerning research and education of doctors in Västra Götaland, Sweden. We thank BMS for supplying dasatinib. We also thank Berit Størdal and Hanne Hella (Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology) for technical assistance. HHH has been an investigator in studies sponsored by Novartis and Bristol-Myers Squibb and is a national coordinator in the Nordic CML Study Group that has received economical support from both companies for investigator-initiated trials. HW has been an investigator in studies sponsored by Novartis and Bristol-Myers Squibb and has received unrestricted research grants from Novartis.

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Correspondence to T Standal.

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Jönsson, S., Hjorth-Hansen, H., Olsson, B. et al. Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro. Leukemia 24, 1357–1359 (2010).

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