Table 2 Known recurrent alterations detected in 203 patients

From: Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients

  del(11q) del(13q) del(17p) trisomy 12
Total number 27 110 9 23
Frequency (%) 13 54 4 11
Number and frequency (%) according to
Hierarchal model 27 (13) 96 (47) 9 (4) 18 (9)
Size range (Mbp) 9.6–55 0.44–76.8 0.98-whole p-arm
Start-stop range (Mbp) 74.6–134.2 29.3–114 whole p-arm
Average size (Mbp) 29.5 4.6
CDR 0.68 Mbp 33.5 kbp 0.98 Mbp
Average number of     
CNAs/sample     
All CNAs 3.6 2 7.3 2.7
CNAs <1 Mbp 0.96 0.7 1.2 0.9
CNAs 1–5 Mbp 0.7 0.78 1.5 0.22
CNAs >5 Mbp 1.96 0.27 4.4 1.6
  1. Abbreviation: CDR, common deleted region.
  2. 53 samples did not carry any of the known recurrent alterations.