Figure 7 | Laboratory Investigation

Figure 7

From: A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

Figure 7

Adjacent serial sections of AD hippocampus stained for pS6 (a) and 8OHG (b). The majority of cells with pS6-positive granules contain visibly less 8OHG (red circles), while 25% of the pS6-positive neurons have 8OHG levels comparable to cells not containing pS6 (black circles). Following quantification of the cytoplasmic levels of 8OHG, cells with pS6-positive granules contain significantly less 8OHG (c, *P<0.01).

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