Figure 2 | Laboratory Investigation

Figure 2

From: The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice

Figure 2

Genetic loss of osteopontin (OPN) and tumor necrosis factor-α receptor-1 (TNFR1) has no impact on hepatic F4/80 and iNOS mRNA expression. PCR for quantification of hepatic F4/80 and iNOS mRNA levels in chow-fed wild type (WT/chow), WT DDC-fed (WT/DDC), OPN knock-out DDC-fed (OPN/DDC), and TNFR1 knock-out DDC-fed (TNFR/DDC) mice using SYBR Green. Please note that despite OPN and TNFR1 loss, DDC-fed mice show comparable expression levels. n = 5 in each group; *P<0.05 chow-fed vs DDC-fed mice.

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