Abstract
A researcher at the author's facility was carrying out a routine surgical procedure in a mouse that was anesthetized with vaporized isoflurane. When the researcher brought an active cauterizer close to the mouse, a flame erupted from the anesthesia nosecone. An investigation concluded that the fire was ignited when the cauterizer came into contact with the oxygen-enriched atmosphere that was streaming from the anesthetic equipment. The author presents recommendations for preventing similar incidents in the future.
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References
Brunson, D.B. in Anesthesia and Analgesia in Laboratory Animals (eds. Kohn, D.F., Wixson, S.K., White, W.J. & Benson, G.J.) ch. 2 (Academic, New York, 1997).
Acknowledgements
I give special thanks to Scott Goeben (Yale Fire Marshal Office), Randina Palmissano (Yale Animal Resources Center) and Julia Merk (Yale Animal Resources Center) for technical assistance in the investigation, to Steven Wilson (Comparative Medicine) for information on rodent physiology and anesthesia and to Cathy King (Yale Environmental Health & Safety) for help with follow-up actions.
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Klein, R. Fire safety recommendations for administration of isoflurane anesthesia in oxygen. Lab Anim 37, 223–224 (2008). https://doi.org/10.1038/laban0508-223
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DOI: https://doi.org/10.1038/laban0508-223
