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In some tissues, anatomical details are relatively simple and easily analyzed histologically. The eye, however, is a complex structure with important regional anatomical variations that make histological interpretation challenging at best. If the orientation of the eye during sectioning is not carefully controlled, it is easy to make erroneous interpretations. For this and other reasons, eye pathology is a recognized subspecialty of pathology.
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Donnelly, T. Reply to 'A closer look: secondary glaucoma more likely'. Lab Anim 36, 14 (2007). https://doi.org/10.1038/laban0107-14
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DOI: https://doi.org/10.1038/laban0107-14