Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • State of the Art
  • Published:

State-of-the-Art

Acupuncture in the neonatal intensive care unit—using ancient medicine to help today’s babies: a review

Abstract

Acupuncture has been used for thousands of years in Eastern medicine for a variety of conditions and illnesses, including pain. Neonatal intensive care, on the other hand, is a relatively new branch of medicine that has emerged as the pivotal influence in increasing survival of critically ill newborn infants only within the last 50 years. Unfortunately, pain is an inevitable part of treatment in a neonatal intensive care unit (NICU). The control and prevention of pain remains a major issue for clinicians despite recognition and understanding of the myriad of short- and long-term problems that are associated with both pain and its treatment within the NICU environment. In this review, we examine the potential role of acupuncture to decrease and treat pain in babies requiring neonatal intensive care and discuss future therapeutic and research implications for the use of this ancient therapy within the modern environment of the NICU.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1

References

  1. Anand KJ, Johnston CC, Oberlander TF, Taddio A, Lehr VT, Walco GA . Analgesia and local anesthesia during invasive procedures in the neonate. Clin Ther 2005; 27 (6): 844–876.

    Article  CAS  PubMed  Google Scholar 

  2. Akuma AO, Jordan S . Pain management in neonates: a survey of nurses and doctors. J Adv Nurs 2012; 68 (6): 1288–1301.

    Article  PubMed  Google Scholar 

  3. Hall RW, Anand KJ . Pain management in newborns. Clin Perinatol 2014; 41 (4): 895–924.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Walker SM . Neonatal pain. Paediatr Anaesth 2014; 24 (1): 39–48.

    Article  PubMed  Google Scholar 

  5. Vinall J, Miller SP, Chau V, Brummelte S, Synnes AR, Grunau RE . Neonatal pain in relation to postnatal growth in infants born very preterm. Pain 2012; 153 (7): 1374–1381.

    Article  PubMed  Google Scholar 

  6. Anand K, Grunau R, Oberlander T . Developmental character and long-term consequences of pain in infants and children. Child Adolesc Psychiatr Clin N Am 1997; 6 (4): 703–724.

    Article  Google Scholar 

  7. World Health Organization. Acupuncture: Review and Analysis of Reports on Controlled Clinical Trials. World Health Organisation: Geneva,2002.

  8. Merskey H, Albe-Fessard D, Bonica J . Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Taxonomy. Pain 1979; 6 (3): 249.

    Google Scholar 

  9. Anand KJ . Clinical importance of pain and stress in preterm neonates. Neonatology 1997; 73 (1): 1–9.

    Article  Google Scholar 

  10. Anand KJ, Hickey PR . Pain and its effects in the human neonate and fetus. N Engl J Med 1987; 317 (21): 1321–1329.

    Article  CAS  PubMed  Google Scholar 

  11. Vinall J, Grunau RE . Impact of repeated procedural pain-related stress in infants born very preterm. Pediatr Res 2014; 75 (5): 584–587.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Fitzgerald M, Walker SM . Infant pain management: a developmental neurobiological approach. Nat Clin Pract Neurol 2009; 5 (1): 35–50.

    Article  PubMed  Google Scholar 

  13. Carbajal R, Rousset A, Danan C, Coquery S, Nolent P, Ducrocq S et al. Epidemiology and treatment of painful procedures in neonates in intensive care units. JAMA 2008; 300 (1): 60–70.

    Article  CAS  PubMed  Google Scholar 

  14. Simons SH, van Dijk M, Anand KS, Roofthooft D, van Lingen RA, Tibboel D . Do we still hurt newborn babies?: a prospective study of procedural pain and analgesia in neonates. Arch Pediatr Adolesc Med 2003; 157 (11): 1058–1064.

    Article  PubMed  Google Scholar 

  15. Cignacco E, Hamers J, van Lingen RA, Stoffel L, Buchi S, Muller R et al. Neonatal procedural pain exposure and pain management in ventilated preterm infants during the first 14 days of life. Swiss Med Wkly 2009; 139 (15): 226.

    CAS  PubMed  Google Scholar 

  16. Rohrmeister K, Kretzer V, Berger A, Haiden N, Kohlhauser C, Pollak A . Pain and stress management in the Neonatal Intensive Care Unit—a national survey in Austria. Wien Klin Wochenschr 2003; 115 (19–20): 715–719.

    Article  PubMed  Google Scholar 

  17. Lago P, Guadagni A, Merazzi D, Ancora G, Bellieni CV, Cavazza A et al. Pain management in the neonatal intensive care unit: a national survey in Italy. Paediatr Anaesth 2005; 15 (11): 925–931.

    Article  PubMed  Google Scholar 

  18. Walker SM . Biological and neurodevelopmental implications of neonatal pain. Clin Perinatol 2013; 40 (3): 471–491.

    Article  PubMed  Google Scholar 

  19. Slater R, Cantarella A, Gallella S, Worley A, Boyd S, Meek J et al. Cortical pain responses in human infants. J Neurosci 2006; 26 (14): 3662–3666.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Bartocci M, Bergqvist LL, Lagercrantz H, Anand KJ . Pain activates cortical areas in the preterm newborn brain. Pain 2006; 122 (1–2): 109–117.

    Article  PubMed  Google Scholar 

  21. Grunau RE, Holsti L, Haley DW, Oberlander T, Weinberg J, Solimano A et al. Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU. Pain 2005; 113 (3): 293–300.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Bouza H . The impact of pain in the immature brain. J Matern Fetal Neonatal Med 2009; 22 (9): 722–732.

    Article  PubMed  Google Scholar 

  23. Golianu B, Krane E, Seybold J, Almgren C, Anand KJ . Non-pharmacological techniques for pain management in neonates. Semin Perinatol 2007; 31 (5): 318–322.

    Article  PubMed  Google Scholar 

  24. Quah-Smith I . Auriculotherapy: alleviating pain and distress in neonates in the intensive care unit. Med Acupunct 2015; 27 (6): 409–410.

    Article  Google Scholar 

  25. Anand KJ, Papanicolaou AC, Palmer FB . Repetitive neonatal pain and neurocognitive abilities in ex‐preterm children. Pain 2013; 154 (10): 1899–1901.

    Article  PubMed  Google Scholar 

  26. Doesburg SM, Chau CM, Cheung TP, Moiseev A, Ribary U, Herdman AT et al. Neonatal pain-related stress, functional cortical activity and visual-perceptual abilities in school-age children born at extremely low gestational age. Pain 2013; 154 (10): 1946–1952.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Grunau RE, Whitfield MF, Petrie-Thomas J, Synnes AR, Cepeda IL, Keidar A et al. Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants. Pain 2009; 143 (1): 138–146.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Valeri BO, Holsti L, Linhares MB . Neonatal pain and developmental outcomes in children born preterm: a systematic review. Clin J Pain 2015; 31 (4): 355–362.

    Article  PubMed  Google Scholar 

  29. Brummelte S, Grunau RE, Chau V, Poskitt KJ, Brant R, Vinall J et al. Procedural pain and brain development in premature newborns. Ann Neurol 2012; 71 (3): 385–396.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Zwicker JG, Grunau RE, Adams E, Chau V, Brant R, Poskitt KJ et al. Score for Neonatal Acute Physiology–II and neonatal pain predict corticospinal tract development in premature newborns. Pediatr Neurol 2013; 48 (2): 123–129 e121.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Anand K, Scalzo FM . Can adverse neonatal experiences alter brain development and subsequent behavior? Neonatology 2000; 77 (2): 69–82.

    Article  CAS  Google Scholar 

  32. van den Bosch GE, White T, El Marroun H, Simons SH, van der Lugt A, van der Geest JN et al. Prematurity, opioid exposure and neonatal pain: do they affect the developing brain. Neonatology 2015; 108 (1): 8–15.

    Article  CAS  PubMed  Google Scholar 

  33. Kesavan K . Neurodevelopmental implications of neonatal pain and morphine exposure. Pediatr Ann 2015; 44 (11): e260–e264.

    Article  PubMed  Google Scholar 

  34. Meek J . Options for procedural pain in newborn infants. Arch Dis Child Educ Pract Ed 2012; 97 (1): 23–28.

    Article  PubMed  Google Scholar 

  35. Carbajal R, Lenclen R, Jugie M, Paupe A, Barton BA, Anand KJ . Morphine does not provide adequate analgesia for acute procedural pain among preterm neonates. Pediatrics 2005; 115 (6): 1494–1500.

    Article  PubMed  Google Scholar 

  36. Simons SH, van Dijk M, van Lingen RA, Roofthooft D, Duivenvoorden HJ, Jongeneel N et al. Routine morphine infusion in preterm newborns who received ventilatory support: a randomized controlled trial. JAMA 2003; 290 (18): 2419–2427.

    Article  CAS  PubMed  Google Scholar 

  37. Anand KJ, Barton BA, McIntosh N, Lagercrantz H, Pelausa E, Young TE et al. Analgesia and sedation in preterm neonates who require ventilatory support: results from the NOPAIN trial. Neonatal Outcome and Prolonged Analgesia in Neonates. Arch Pediatr Adolesc Med 1999; 153 (4): 331–338.

    Article  CAS  PubMed  Google Scholar 

  38. Stevens B, Yamada J, Haliburton S, Ohlsson A, Shorkey A . Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev 2016; (7): CD001069.

  39. Johnston C, Campbell-Yeo M, Fernandes A, Inglis D, Streiner D, Zee R . Skin-to-skin care for procedural pain in neonates. Cochrane Database Syst Rev 2014; (1): CD008435.

  40. Shah P, Herbozo C, Aliwalas L, Shah V . Breastfeeding or breast milk for procedural pain in neonates. Cochrane Database Syst Rev 2012; (12): CD004950.

  41. Schuurmans J, Benders M, Lemmers P, van Bel F . Neonatal morphine in extremely and very preterm neonates: its effect on the developing brain—a review. J Matern Fetal Neonatal Med 2015; 28 (2): 222–228.

    Article  CAS  PubMed  Google Scholar 

  42. Bellu R, de Waal KA, Zanini R . Opioids for neonates receiving mechanical ventilation. Cochrane Database Syst Rev 2008; (1):Article ID CD004212.

  43. Bajic D, Commons KG, Soriano SG . Morphine-enhanced apoptosis in selective brain regions of neonatal rats. Int J Dev Neurosci 2013; 31 (4): 258–266.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Juul SE, Beyer RP, Bammler TK, Farin FM, Gleason CA . Effects of neonatal stress and morphine on murine hippocampal gene expression. Pediatr Res 2011; 69 (4): 285–292.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. Dührsen L, Simons SH, Dzietko M, Genz K, Bendix I, Boos V et al. Effects of repetitive exposure to pain and morphine treatment on the neonatal rat brain. Neonatology 2012; 103 (1): 35–43.

    Article  PubMed  CAS  Google Scholar 

  46. de Graaf J, van Lingen RA, Valkenburg AJ, Weisglas-Kuperus N, Jebbink LG, Wijnberg-Williams B et al. Does neonatal morphine use affect neuropsychological outcomes at 8 to 9 years of age? Pain 2013; 154 (3): 449–458.

    Article  CAS  PubMed  Google Scholar 

  47. Ferguson SA, Ward WL, Paule MG, Hall RW, Anand K . A pilot study of preemptive morphine analgesia in preterm neonates: effects on head circumference, social behavior, and response latencies in early childhood. Neurotoxicol Teratol 2012; 34 (1): 47–55.

    Article  CAS  PubMed  Google Scholar 

  48. de Graaf J, van Lingen RA, Simons SH, Anand KJ, Duivenvoorden HJ, Weisglas-Kuperus N et al. Long-term effects of routine morphine infusion in mechanically ventilated neonates on children’s functioning: five-year follow-up of a randomized controlled trial. Pain 2011; 152 (6): 1391–1397.

    Article  CAS  PubMed  Google Scholar 

  49. MacGregor R, Evans D, Sugden D, Gaussen T, Levene M . Outcome at 5–6 years of prematurely born children who received morphine as neonates. Arch Dis Child Fetal and Neonatal Ed 1998; 79 (1): F40–F43.

    Article  CAS  Google Scholar 

  50. Steinhorn R, McPherson C, Anderson PJ, Neil J, Doyle LW, Inder T . Neonatal morphine exposure in very preterm infants—cerebral development and outcomes. J Pediatr 2015; 166 5: 1200–1207;e1204.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  51. Ranger M, Synnes A, Vinall J, Grunau R . Internalizing behaviours in school‐age children born very preterm are predicted by neonatal pain and morphine exposure. Eur J Pain 2014; 18 (6): 844–852.

    Article  CAS  PubMed  Google Scholar 

  52. Härmä A, Aikio O, Hallman M, Saarela T . Intravenous paracetamol decreases requirements of morphine in very preterm infants. J Pediatr 2016; 168: 36–40.

    Article  PubMed  CAS  Google Scholar 

  53. Taddio A, Shah V, Hancock R, Smith RW, Stephens D, Atenafu E et al. Effectiveness of sucrose analgesia in newborns undergoing painful medical procedures. Can Med Assoc J 2008; 179 (1): 37–43.

    Article  Google Scholar 

  54. Johnston CC, Filion F, Snider L, Majnemer A, Limperopoulos C, Walker C-D et al. Routine sucrose analgesia during the first week of life in neonates younger than 31 weeks’ postconceptional age. Pediatrics 2002; 110 (3): 523–528.

    Article  PubMed  Google Scholar 

  55. Chon TY, Lee MC . Acupuncture. Mayo Clin Proc 2013; 88 (10): 1141–1146.

    Article  PubMed  Google Scholar 

  56. Vickers A, Zollman C . ABC of complementary medicine: acupuncture. Br Med J 1999; 319 (7215): 973.

    Article  CAS  Google Scholar 

  57. Lin J-G, Chen W-L . Acupuncture analgesia: a review of its mechanisms of actions. Am J Chin Med 2008; 36 (04): 635–645.

    Article  CAS  PubMed  Google Scholar 

  58. Tracey KJ . The inflammatory reflex. Nature 2002; 420 (6917): 853–859.

    Article  CAS  PubMed  Google Scholar 

  59. Colbert AP, Cleaver J, Brown KA, Harling N, Hwang Y, Schiffke HC et al. Magnets applied to acupuncture points as therapy—a literature review. Acupunct Med 2008; 26 (3): 160–170.

    Article  PubMed  Google Scholar 

  60. McKay JC, Prato FS, Thomas AW . A literature review: the effects of magnetic field exposure on blood flow and blood vessels in the microvasculature. Bioelectromagnetics 2007; 28 (2): 81–98.

    Article  CAS  PubMed  Google Scholar 

  61. Morris CE, Skalak TC . Chronic static magnetic field exposure alters microvessel enlargement resulting from surgical intervention. J Appl Physiol 2007; 103 (2): 629–636.

    Article  PubMed  Google Scholar 

  62. McLean M, Holcomb R, Wamil A, Pickett JD, Cavopol A . Blockade of sensory neuron action potentials by a static magnetic field in the 10 mT range. Bioelectromagnetics 1995; 16 (1): 20–32.

    Article  CAS  PubMed  Google Scholar 

  63. White A . A cumulative review of the range and incidence of significant adverse events associated with acupuncture. Acupunct Med 2004; 22 (3): 122–133.

    Article  PubMed  Google Scholar 

  64. Lee MS, Ernst E . Acupuncture for pain: an overview of Cochrane reviews. Chin J Integr Med 2011; 17 (3): 187–189.

    Article  PubMed  Google Scholar 

  65. Jindal V, Ge A, Mansky PJ . Safety and efficacy of acupuncture in children a review of the evidence. J Pediatr Hematol Oncol 2008; 30 (6): 431.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Baxter GD, Bleakley C, McDonough S . Clinical effectiveness of laser acupuncture: a systematic review. J Acupunct Meridian Stud 2008; 1 (2): 65–82.

    Article  PubMed  Google Scholar 

  67. Ernst E, White AR . Prospective studies of the safety of acupuncture: a systematic review. Am J Med 2001; 110 (6): 481–485.

    Article  CAS  PubMed  Google Scholar 

  68. Ecevit A, Ince DA, Tarcan A, Cabioglu MT, Kurt A . Acupuncture in preterm babies during minor painful procedures. J Tradit Chin Med 2011; 31 (4): 308–310.

    Article  PubMed  Google Scholar 

  69. Abbasoglu A, Cabioglu MT, Tugcu AU, Ince DA, Tekindal MA, Ecevit A et al. Acupressure at BL60 and K3 points before heel lancing in preterm infants. Explore (NY) 2015; 11 (5): 363–366.

    Article  Google Scholar 

  70. Yates CC, Mitchell AJ, Lowe LM, Lee A, Hall RW . Safety of noninvasive electrical stimulation of acupuncture points during a routine neonatal heel stick. Med Acupunct 2013; 25 (4): 285–290.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Chen LL, Su YC, Su CH, Lin HC, Kuo HW . Acupressure and meridian massage: combined effects on increasing body weight in premature infants. J Clin Nurs 2008; 17 (9): 1174–1181.

    Article  PubMed  Google Scholar 

  72. Gentry KR, McGinn KL, Kundu A, Lynn AM . Acupuncture therapy for infants: a preliminary report on reasons for consultation, feasibility, and tolerability. Paediatr Anaesth 2012; 22 (7): 690–695.

    Article  PubMed  Google Scholar 

  73. Golianu B, Seybold J, Almgren C . Acupuncture helps reduce need for sedative medications in neonates and infants undergoing treatment in the Intensive Care Unit: a prospective case series. Med Acupunct 2014; 26 (5): 279–285.

    Article  Google Scholar 

  74. Schwartz L, Xiao R, Brown ER, Sommers E . Auricular acupressure augmentation of standard medical management of the neonatal narcotic abstinence syndrome. Med Acupunct 2011; 23 (3): 175–186.

    Article  Google Scholar 

  75. Filippelli AC, White LF, Spellman LW, Broderick M, Highfield ES, Sommers E et al. Non-insertive acupuncture and neonatal abstinence syndrome: a case series from an inner-city safety net hospital. Global Adv Health Med 2012; 1 (4): 48–52.

    Article  Google Scholar 

  76. Raith W, Resch B, Urlesberger B . Laser acupuncture as adjuvant treatment of neonates suffering from abstinence symptoms due to maternal substitution therapy: Initial findings from a pilot study. DZA 2014; 57 (3): 12–17.

    Google Scholar 

  77. Raith W, Schmolzer GM, Resch B, Reiterer F, Avian A, Koestenberger M et al. Laser acupuncture for neonatal abstinence syndrome: a randomized controlled trial. Pediatrics 2015; 136 (5): 876–884.

    Article  PubMed  Google Scholar 

  78. Weathers L, Driver K, Zaritt J, Kneusel M, Reinhart R, Roberts S et al. Safety, acceptability, and feasibility of auricular acupuncture in neonatal abstinence syndrome: a pilot study. Med Acupunct 2015; 27 (6): 453–460.

    Article  Google Scholar 

  79. Landgren K, Kvorning N, Hallstrom I . Feeding, stooling and sleeping patterns in infants with colic—a randomized controlled trial of minimal acupuncture. BMC Complement Altern Med 2011; 11 (1): 93–101.

    Article  PubMed  PubMed Central  Google Scholar 

  80. Reinthal M, Lund I, Ullman D, Lundeberg T . Gastrointestinal symptoms of infantile colic and their change after light needling of acupuncture: a case series study of 913 infants. Chin Med 2011; 6 (1): 28–37.

    Article  PubMed  PubMed Central  Google Scholar 

  81. Reinthal M, Andersson S, Gustafsson M, Plos K, Lund I, Lundeberg T et al. Effects of minimal acupuncture in children with infantile colic—a prospective, quasi-randomised single blind controlled trial. Acupunct Med 2008; 26 (3): 171–182.

    Article  PubMed  Google Scholar 

  82. Skjeie H, Skonnord T, Fetveit A, Brekke M . A pilot study of ST36 acupuncture for infantile colic. Acupunct Med 2011; 29 (2): 103–107.

    Article  PubMed  Google Scholar 

  83. Ding D . Treatment of infantile diarrhea by acupuncture and laser irradiation—a report of 60 cases. J Tradit Chin Med 2004; 24 (4): 280–281.

    PubMed  Google Scholar 

  84. Raith W, Litscher G, Sapetschnig I, Bauchinger S, Ziehenberger E, Muller W et al. Thermographical measuring of the skin temperature using laser needle acupuncture in preterm neonates. Evid Based Complementary Altern Med 2012; 2012:, Article ID 614210, 5 pages. doi:10.1155/2012/614210.

    Article  Google Scholar 

  85. Kurath-Koller S, Litscher G, Gross A, Freidl T, Koestenberger M, Urlesberger B et al. Changes of locoregional skin temperature in neonates undergoing laser needle acupuncture at the acupuncture point large intestine 4. Evid Based Complementary Altern Med 2015; 2015, Article ID: 571857.

  86. Thiel MT, Stockert K . Acupuncture and neonatology. J Chin Med 2011; (97): 50–53.

  87. Raith W, Urlesberger B, Schmolzer GM . Efficacy and safety of acupuncture in preterm and term infants. Evid Based Complementary Altern Med 2013; 2013, Article ID 739414.

  88. Raith W, Litscher G, Muller W, Urlesberger B . Laseracupuncture—a possible alternative treatment for agitation and pain in neonates? Paediatr Anaesth 2013; 23 (2): 205–206.

    Article  PubMed  Google Scholar 

  89. Van Ämerongen KS, Blattmann FC, Kuhn A, Surbek D, Nelle M . Ear acupuncture points in neonates. J Altern Complementary Med 2008; 14 (1): 47–52.

    Article  Google Scholar 

  90. Raith W, Kutschera J, Muller W, Urlesberger B . Active ear acupuncture points in neonates with neonatal abstinence syndrome (NAS). Am J Chin Med 2011; 39 (1): 29–37.

    Article  PubMed  Google Scholar 

  91. Zeltzer LK, Tsao JC, Stelling C, Powers M, Levy S, Waterhouse M . A phase I study on the feasibility and acceptability of an acupuncture/hypnosis intervention for chronic pediatric pain. J Pain Symptom Manage 2002; 24 (4): 437–446.

    Article  PubMed  Google Scholar 

  92. MacPherson H, Altman DG, Hammerschlag R, Youping L, Taixiang W, White A et al. Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. PLoS Med 2010; 7 (6): e1000261.

    Article  PubMed  PubMed Central  Google Scholar 

  93. Schulz KF, Altman DG, Moher D . CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. BMC Med 2010; 8 (1):1–9.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J L Oei.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Additional information

Author contributions

KLC developed first draft of manuscript, revised and manuscript for submission; IQ-S, GMS and RN reviewed, revised and approved manuscript for submission; JLO developed concept for study, supervised KLC, revised and approved final manuscript for submission.

Disclaimer

The opinions and assertions contained herein are the private views of the author and are not to be construed as official or as reflecting the views of the United States Air Force Medical Corps, the Air Force at large, or the Department of Defense.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, K., Quah-Smith, I., Schmölzer, G. et al. Acupuncture in the neonatal intensive care unit—using ancient medicine to help today’s babies: a review. J Perinatol 37, 749–756 (2017). https://doi.org/10.1038/jp.2016.227

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jp.2016.227

Search

Quick links