Table 2 Maternal serum markers: placenta previa with and without MAP, n=736

From: Maternal serum markers, characteristics and morbidly adherent placenta in women with previa

  Previa alone (n=699) Previa with MAP (n=37) OR (95% CI)
First trimester biomarkers (MoM)
PAPP-A, n (%)
5th % (0.38) 41 (5.9) 1 (2.7) 0.5 (0.1–3.8)
6th–94th % (0.39–2.62) 621 (88/8) 30 (81.1) Reference
95th % (2.63) 37 (5.3) 6 (16.2) 3.4 (1.3–8.6)*
hCG, n (%)
5th % (0.50) 33 (4.7) 1 (2.7) 0.6 (0.1–4.3)
6th–94th % (0.51–1.99) 625 (89.4) 33 (89.2) Reference
95th % (2.00) 41 (5.9) 3 (8.1) 1.4 (0.4–4.7)
Second trimester biomarkers (MoM)
MS-AFP, n(%)
5th % (0.60) 20 (2.9) 0 (0.0) a
6th–94th % (0.61–1.78) 633 (90.6) 30 (81.1) Reference
95th % (1.79) 46 (6.6) 7 (18.9) 3.2 (1.3–7.7)**
hCG, n (%)
5th % (0.41) 33 (4.7) 0 (0.0) a
6th–94th % (0.42–2.27) 631 (90.3) 35 (94.6) Reference
95th % (2.28) 35 (5.0) 2 (5.4) 1.0 (0.2–4.5)
 uE3, n (%)
5th % (0.63) 42 (6.0) 1 (2.7) 0.4 (0.1–3.2)
6th–94th % (0.64–1.39) 630 (90.1) 35 (94.6) Reference
95th % (1.40) 27 (3.9) 1 (2.7) 0.7 (0.1–5.0)
 INH, n (%)
5th % (0.54) 23 (3.3) 0 (0.0) a
6th–94th % (0.55–2.13) 627 (89.7) 34 (91.9) Reference
95th % (2.14) 49 (7.0) 3 (8.3) 1.1 (0.3–3.8)
  1. Abbreviations: CI, confidence interval; hCG, human chorionic gonadotropin; INH, inhibin A; MAP, morbidly adherent placenta; MoM, multiple of the median; MS, maternal serum; OR, odds ratio; PAPP-A, pregnancy-associated plasma protein-A; uE3, unconjugated estriol. *P<0.05; **P<0.01.
  2. aNot computed.