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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Arterial hypotension and prerenal failure in an extremely preterm infant associated with oral sildenafil

Journal of Perinatology volume 35, pages 458–459 (2015)Cite this article

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Abstract

We report significant hypotension and prerenal failure in an extremely preterm infant following two doses of oral sildenafil that warranted discontinuation of the drug and treatment with inotropes. Blood pressure and urine output normalized after 24 h of withdrawal of the oral drug. Sildenafil should be used cautiously in extremely preterm infants early in the neonatal course, where there is limited data on its efficacy and safety.

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Authors and Affiliations

  1. Neonatal Clinical Care Unit, King Edward Memorial Hospital for Women, Perth, WA, Australia

    H Balasubramanian, T Strunk & R Kohan

  2. Centre for Neonatal Research and Education, School of Paediatrics and Child Health University of Western Australia, Perth, WA, Australia

    T Strunk & R Kohan

Authors
  1. H Balasubramanian
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  2. T Strunk
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  3. R Kohan
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Correspondence to H Balasubramanian.

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Balasubramanian, H., Strunk, T. & Kohan, R. Arterial hypotension and prerenal failure in an extremely preterm infant associated with oral sildenafil. J Perinatol 35, 458–459 (2015). https://doi.org/10.1038/jp.2015.31

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  • DOI: https://doi.org/10.1038/jp.2015.31

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