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One-time umbilical cord milking after cord cutting has same effectiveness as multiple-time umbilical cord milking in infants born at <29 weeks of gestation: a retrospective study

Journal of Perinatology volume 35, pages 590–594 (2015)Cite this article

Subjects

Abstract

Objective:

To compare two strategies to potentiate the effects of placental transfusion in infants born at <29 weeks of gestation.

Study design:

Twenty infants who received one-time umbilical cord milking after umbilical cord cutting were compared with 20 infants from a previous study group who received multiple-time umbilical cord milking. The primary outcome measurements were the probability of not needing a red blood cell (RBC) transfusion during the hospital stay and the total number of RBC transfusions within 21 days after birth.

Result:

There was no significant difference in the probability of not needing a transfusion during the hospital stay (P=0.75) and the mean number of RBC transfusions given within the first 21 days of life (1.1±1.8 for the one-time umbilical cord-milking group vs 0.7±1.2 for the multiple-time umbilical cord-milking group, P=0.48).

Conclusion:

One-time umbilical cord milking after umbilical cord cutting had similar beneficial effects to multiple-time umbilical cord milking before umbilical cord cutting in very premature infants.

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Acknowledgements

This work was supported by MEXT KAKENHI (Grant-in-Aid for Scientific Research (C) Grant Number 26461649.

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Authors and Affiliations

  1. Division of Neonatology, Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan

    S Hosono, H Mugishima, S Takahashi & S Takahashi

  2. Department of Obstetrics and Gynecology, Tokyo Women’s Medical University Yachiyo Medical Center, Chiba, Japan

    N Masaoka

  3. Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan

    N Masaoka & T Yamamoto

  4. Division of Neonatal Medicine, Center for Maternal, Fetal and Neonatal Medicine, Saitama Medical University Kawagoe Medical Center, Saitama, Japan

    M Tamura

Authors
  1. S Hosono
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  2. H Mugishima
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  3. S Takahashi
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  4. S Takahashi
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  5. N Masaoka
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  6. T Yamamoto
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  7. M Tamura
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Corresponding author

Correspondence to S Hosono.

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Hosono, S., Mugishima, H., Takahashi, S. et al. One-time umbilical cord milking after cord cutting has same effectiveness as multiple-time umbilical cord milking in infants born at <29 weeks of gestation: a retrospective study. J Perinatol 35, 590–594 (2015). https://doi.org/10.1038/jp.2015.15

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  • DOI: https://doi.org/10.1038/jp.2015.15

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