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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Pulmonary artery thrombus in a premature neonate treated with recombinant tissue plasminogen activator

Journal of Perinatology volume 34, pages 569–571 (2014)Cite this article

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Abstract

Pulmonary artery thrombus is a rarely reported complication in premature neonates. The management of life-threatening thrombotic events in neonates is controversial, especially regarding the use of thrombolytics versus anticoagulation alone for treatment. We report a case of a premature neonate with symptomatic pulmonary artery thrombus treated with recombinant tissue plasminogen activator who survived without bleeding complications.

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Acknowledgements

We thank Dr Christoph Hornik and Dr Piers C Barker for providing echocardiogram images and videos.

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Authors and Affiliations

  1. Division of Neonatology, Duke University Medical Center, Durham, NC, USA,

    S D DeMeo, R N Goldberg, C M Cotten & M Bidegain

  2. Division of Neonatology, University of North Carolina, Chapel Hill, NC, USA

    A Sherwood

  3. Department of Pharmacy, Duke University Medical Center, Durham, NC, USA,

    C D Hornik

Authors
  1. S D DeMeo
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  2. A Sherwood
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  3. C D Hornik
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  4. R N Goldberg
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  5. C M Cotten
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  6. M Bidegain
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Corresponding author

Correspondence to S D DeMeo.

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The authors declare no conflict of interest.

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Supplementary Information accompanies the paper on the Journal of Perinatology website

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DeMeo, S., Sherwood, A., Hornik, C. et al. Pulmonary artery thrombus in a premature neonate treated with recombinant tissue plasminogen activator. J Perinatol 34, 569–571 (2014). https://doi.org/10.1038/jp.2014.34

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  • DOI: https://doi.org/10.1038/jp.2014.34

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