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References
Espinasse M, Manouvrier S, Boute O, Farriaux JP . Embryofetopathie au valproate: unepathologie encore trop mal connue. A propos de quatre observations. Arch Pedia 1996; 3: 896–899.
Bailey CJ, Pool RW, Poskitt EM, Harris F . Valproic acid and fetal abnormality. Br Med J (Clin Res Ed) 1983; 286 (6360): 190.
DiLiberti JH, Farndon PA, Dennis NR, Curry CJ . The fetal valproate syndrome. Am J Med Genet 1984; 19: 473–481.
Kozma C . Valproic acid emptryopathy: report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature. Am J Med Genet 2001; 98: 168–175.
Ozkan H, Cetinkaya M, Koksal N, Yapici S . Severe fetal valproate syndrome: combination of complex cardiac defect, multicystic dysplastic kidney and trigonencephaly. J Maternal-Fetal Neonatal Med 2011; 24: 521–524.
Ornoy A . Valproic acid in pregnancy: how much are we endangering the embryo and fetus? Reprod Toxicol 2009; 28: 1–10.
Vajda FJ, O'Brien TJ, Graham JE, Lander CM, Eadie MJ . Dose dependence of fetal malformations associated with valproate. Neurology 2013; 81: 999–1003.
Vajda FJ, O'Brien TJ, Graham J, Lander CM, Eadie MJ . Associations between particular types of fetal malformation and antiepileptic drug exposure in utero. Acta Neurol Scand 2013; 128: 228–234.
Alessandri JL, Isidor B, David A, Martin-Coignard D, Ghazouani J, Ramful D et al. Tibial developmental field defect in valproic acid embryopathy: Report on three cases. Am J Med Genet A 2010; 152A: 2805–2809.
Zaki SA, Phulsundar A, Shanbag P, Mauskar A . Fetal valproate syndrome in a 2-month-old male infant. Ann Saudi Med 2010; 30: 233–235.
Kini U . Fetal valproate syndrome: a review. Paediatr Perinat Drug Ther 2006; 7: 123–130.
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Sargar, K., Herman, T. & Siegel, M. Valproate fetopathy. J Perinatol 35, 82–83 (2015). https://doi.org/10.1038/jp.2014.158
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DOI: https://doi.org/10.1038/jp.2014.158
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