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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Limb hypoplasia resulting from intrauterine infection with herpes simplex virus: a case report

Journal of Perinatology volume 34, pages 873–874 (2014)Cite this article

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Abstract

Intrauterine infection with herpes simplex virus, although very rare, has devastating effects on multiple organ systems in the fetus and can lead to in utero fetal demise. Neonates born following intrauterine herpes simplex virus infection commonly manifest with cutaneous lesions, ocular damage and/or brain abnormalities. We describe the case of a dichorionic, diamniotic twin gestation complicated by intrauterine herpes simplex virus infection. This infection led to the fetal demise of twin A and a very uncommon presentation of limb hypoplasia in twin B.

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Authors and Affiliations

  1. Division of Neonatology, Nemours at Thomas Jefferson University, Philadelphia, PA, USA

    D Carola, M Skibo & Z H Aghai

  2. Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA, USA

    S Cannon, K M Cam & P Hyde

  3. Department of Pediatric Dermatology, Nemours/A.I. Dupont Hospital for Children, Wilmington, DE, USA

    P Hyde

Authors
  1. D Carola
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  2. M Skibo
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  3. S Cannon
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  4. K M Cam
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  5. P Hyde
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  6. Z H Aghai
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Correspondence to D Carola.

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The authors declare no conflicts of interest.

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Carola, D., Skibo, M., Cannon, S. et al. Limb hypoplasia resulting from intrauterine infection with herpes simplex virus: a case report. J Perinatol 34, 873–874 (2014). https://doi.org/10.1038/jp.2014.121

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  • DOI: https://doi.org/10.1038/jp.2014.121

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