Abstract
The combined Poland and Mobius syndrome occurs rarely and with a wide range of features. There is no consensus on the etiology of this syndrome; familial, sporadic cases and likely environmental insult cases have been reported. This sporadic case represents a unique variant in the spectrum of this syndrome.
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References
David TJ . Nature and etiology of the Poland anomaly. N Engl J Med 1972; 287 (10): 487–489.
Darian VB, Argenta LC, Pasyk KA . Familial Poland's syndrome. Ann Plast Surg 1989; 23 (6): 531–537.
Al-Qattan MM . Classification of hand anomalies in Poland's syndrome. Br J Plast Surg 2001; 54 (2): 132–136.
Van Allen MW, Blodi FC . Neurologic aspects of the Mobius syndrome. A case study with electromyography of the extraocular and facial muscles. Neurology 1960; 10: 249–259.
Sugarman GI, Stark HH . Mobius syndrome with Poland's anomaly. J Med Genet 1973; 10 (2): 192–196.
Bosch-Banyeras JM, Zuasnabar A, Puig A, Catala M, Cuatrecasas JM . Poland-Mobius syndrome associated with dextrocardia. J Med Genet 1984; 21 (1): 70–71.
Puvabanditsin S, Garrow E, Augustin G, Titapiwatanakul R, Kuniyoshi KM . Poland-Mobius syndrome and cocaine abuse: a relook at vascular etiology. Pediatr Neurol 2005; 32 (4): 285–287.
Kremer H, Kuyt LP, van den Helm B, van Reen M, Leunissen JA, Hamel BC et al. Localization of a gene for Mobius syndrome to chromosome 3q by linkage analysis in a Dutch family. Hum Mol Genet 1996; 5 (9): 1367–1371.
Verzijl HT, van den Helm B, Veldman B, Hamel BC, Kuyt LP, Padberg GW et al. A second gene for autosomal dominant Mobius syndrome is localized to chromosome 10q, in a Dutch family. Am J Hum Genet 1999; 65 (3): 752–756.
Rojas-Martinez A, Garcia-Cruz D, Rodriguez Garcia A, Sanchez-Corona J, Rivas F . Poland-Moebius syndrome in a boy and Poland syndrome in his mother. Clin Genet 1991; 40 (3): 225–228.
Pachajoa H, Isaza C . First case of Moebius-Poland syndrome in child prenatally exposed to misoprostol. Neurologia 2011; 26 (8): 502–503.
Bavinck JN, Weaver DD . Subclavian artery supply disruption sequence: hypothesis of a vascular etiology for Poland, Klippel-Feil, and Mobius anomalies. Am J Med Genet 1986; 23 (4): 903–918.
St Charles S, DiMario Jr FJ, Grunnet ML . Mobius sequence: further in vivo support for the subclavian artery supply disruption sequence. Am J Med Genet 1993; 47 (2): 289–293.
Baraitser M . Genetics of Mobius syndrome. J Med Genet 1977; 14 (6): 415–417.
Graziadio C, Lorenzen MB, Rosa RF, Pinto LL, Zen PR, Travi GM et al. New report of a familial case of Moebius syndrome presenting skeletal findings. Am J Med Genet A 2010; 152A (8): 2134–2138.
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We gratefully acknowledge Dr Chetan Moorthy for the imaging studies done on this patient.
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Flores, A., Ross, J., Tullius, T. et al. A unique variant of Poland–Mobius syndrome with dextrocardia and a 3q23 gain. J Perinatol 33, 572–573 (2013). https://doi.org/10.1038/jp.2012.92
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DOI: https://doi.org/10.1038/jp.2012.92
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