Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Imaging Case Report
  • Published:

Type 2 sacrococcygeal teratoma endodermal sinus tumor

Journal of Perinatology volume 31, pages 804–806 (2011)Cite this article

Subjects

Histological examination of the resected tumor and coccyx demonstrated malignant teratoma with extensive endodermal sinus tumor and tumor at the resected margins.

SCT is the most common neoplasm found in newborns, occurring with a striking female predominance of 4 to 6:1 (ref. 1). The tumor arises from embryonic blastema present in the human tail bud, which normally regresses by 32 to 35 days of gestation.2 Sacrococcygeal teratomas have been shown to be an interesting source of human stem cells.2 To guarantee resection of this embryonic blastema, thus reducing the risk of recurrence, coccygectomy is performed at the time of tumor resection. There is a 37% rate of recurrence of sacrococcygeal teratomas if concomitant coccygectomy is not performed.3

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1
Figure 2

References

  1. Gabra JP, Jesudason EC, McDowell HP, Pizer BL, Losty PD . Sacrococcygeal teratoma – a 25 year experience in a UK regional center. J Pediatr Surg 2006; 41: 1513–1516.

    Article  Google Scholar 

  2. Busch C, Bareiss PM, Sinnberg T, Just L, Wehrmann M, Fuchs J et al. Isolation of three stem cell lines from human sacrococcygeal teratomas. J Pathol 2009; 217: 589–596.

    Article  CAS  Google Scholar 

  3. Ein SH, Mancer K, Debo Adenyemi S . Malignant sacrococcygeal teratoma – endodermal sinus, yolk sac tumor – in infants and children: 32 year review. J Pediatr Surg 1985; 20: 473–477.

    Article  CAS  Google Scholar 

  4. Kaneyama K, Yamataka A, Kobayashi H, Lane GL, Itoh S, Kinoshita K et al. Giant highly vascular sacrococcygeal teratoma; report of its excision using the ligaSure vessel sealing system. J Pediatr Surg 2004; 39: 1791–1793.

    Article  Google Scholar 

  5. Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD et al. Sacrococcygeal teratoma: prenatal assessment, fetal intervention and outcome. J Pediatr Surg 2004; 39: 430–438.

    Article  Google Scholar 

  6. DeBacker A, Madern GC, Hakvoort-Cammel FGAJ, Haentjens P, Oosterhuis JW, Hazebrok FWJ . Study of factors associated with recurrence in children with sacrococcygeal teratoma. J Pediatr Surg 2006; 41: 173–181.

    Article  Google Scholar 

  7. Barreto MWG, Silva LV, Barini R, Oliveira-Filho AG, Sbragia L . Alpha-fetoprotein following neonatal resection of sacrococcygeal teratoma. Pediatr Hematol Oncol 2006; 23: 287–291.

    Article  CAS  Google Scholar 

  8. Draper H, Chitayat D, Ein SH, Langer JC . Long-term functional results following resection of neonatal sacrococcygeal teratoma. Pediatr Surg Int 2009; 25: 243–246.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA

    T E Herman & M J Siegel

Authors
  1. T E Herman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M J Siegel
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to T E Herman.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Herman, T., Siegel, M. Type 2 sacrococcygeal teratoma endodermal sinus tumor. J Perinatol 31, 804–806 (2011). https://doi.org/10.1038/jp.2011.30

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jp.2011.30

Search

Advanced search

Quick links