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Prenatally diagnosed left ventricular diverticulum with thoracoabdominal wall defect: a case and review of the literature

Journal of Perinatology volume 30, pages 760–762 (2010)Cite this article

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Congenital ventricular outpouchings include congenital ventricular diverticulum (CVD) and congenital ventricular aneurysm (CVA).1 Because of the low prevalence of the disease, the two terms have been used interchangeably.2 The definition, the clinical characteristics and the prognosis of the diseases is not certain until now.3, 4 Thus, we add a case of CVD, confirmed following autopsy, with antenatal 2D and 3D ultrasonographic findings and postmortem autopsy findings.

The CVD is a form of extracardiac outpouching. Histologically, it is divided into fibrous and muscular diverticulum. According to the location, it is divided into apical and non-apical type. The CVD differs from CVA in that diverticulum has synchronous contractibility, and has intact myocardial layer. Apical CVD can be defined as a fingerlike contractile pouch with narrow connection to the ventricle. Apical CVD is frequently associated with other intracardiac anomaly and/or midline defect. Both CVD and CVA are very rare, so no data on incidence or prevalence is available.3, 5 Thus, little is known about the etiology of these diseases, but it is said that apical CVD is a part of a syndrome of thoracoabdominal defect with other intracardiac malformations, such as the Cantrell syndrome.6 They said that apical CVD resulted from abnormal fusion of the cardiac loop to the yolk sac with a simultaneous failure of fusion of the paired primitive mesoderm.6, 7

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea

    K H Nam, J Y Kwon, G H Son, Y W Park & Y H Kim

  2. Department of Pathology, Yonsei University College of Medicine, Seoul, Korea

    N H Cho

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Correspondence to Y H Kim.

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Nam, K., Kwon, J., Son, G. et al. Prenatally diagnosed left ventricular diverticulum with thoracoabdominal wall defect: a case and review of the literature. J Perinatol 30, 760–762 (2010). https://doi.org/10.1038/jp.2010.106

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