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A lack of day-by-day variability in blood pressure in a Cushing’s disease patient

Journal of Human Hypertension volume 31, pages 602–603 (2017)Cite this article

Subjects

A 64-year-old Japanese man was diagnosed as Cushing’s disease due to a pituitary adenoma, and Hardy’s operation was performed. After the surgery, his blood pressure (BP) was normalized along with the increase in coefficient of variation (CV) of his self-monitored systolic BP at home from 2.7% to 4.2% and the diastolic BP CV from 3.2% to 5.4%. Diminished BP fluctuation evaluated by home BP monitoring could be a marker of a special cause of hypertension such as secondary hypertension.

The mortality rate of individuals with Cushing’s syndrome is twice that of the general population, and the incidence of cardiovascular disease is twofold to fourfold higher in Cushing’s syndrome patients compared with individuals without this syndrome.1 Hypertension is observed in approximtely 80% of individuals with Cushing’s syndrome, and the hypertension is often difficult to treat.2

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Authors and Affiliations

  1. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan

    K Eguchi & K Kario

  2. Department of Neurosurgery, International University of Health and Welfare Hospital, Tokyo, Japan

    H Kurita, E Matsumoto & M Hashimoto

Authors
  1. K Eguchi
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  2. H Kurita
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  3. E Matsumoto
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  4. M Hashimoto
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  5. K Kario
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Corresponding author

Correspondence to K Eguchi.

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The authors declare no conflict of interest.

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Eguchi, K., Kurita, H., Matsumoto, E. et al. A lack of day-by-day variability in blood pressure in a Cushing’s disease patient. J Hum Hypertens 31, 602–603 (2017). https://doi.org/10.1038/jhh.2017.21

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