Circulating serum (a) tTG, (b) sFlt-1, (c) sEng and (d) VEGF levels in normotensive pregnant women, women with mild PE and women with severe PE. Serum tTG, sFlt-1 and sEng levels are increased, but VEGF levels are decreased in the mild PE and severe PE compared with normotensive pregnant women. ##P<0.001, severe PE and mild PE vs NT. **P<0.001, severe PE vs mild PE. A full colour version of this figure is available at the Journal of Human Hypertension journal online.