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Investigating the effect of transcendental meditation on blood pressure: a systematic review and meta-analysis

Abstract

Some evidence from previous randomized controlled trials and systematic reviews has demonstrated a positive association between hypertension and transcendental meditation (TM). However, other trials and reviews showed the effect of TM on blood pressure (BP) was unclear but did not use subgroup analysis to rigorously investigate this relationship. The American Heart Association has stated that TM is potentially beneficial but did not give a standard indication. The present study explored several subgroup analyses in systematic reviews to investigate the effect of TM on BP. Medline, Embase, Cochrane Library, Web of Science and Chinese BioMedical Literature Database were searched through August 2014. Randomized controlled trials of TM as a primary intervention for BP were included. Two reviewers independently used the Cochrane Collaboration’s quality assessment tool to assess each study’s quality. Twelve studies with 996 participants indicated an approximate reduction of systolic and diastolic BP of −4.26 mm Hg (95% CI=−6.06, −2.23) and −2.33 mm Hg (95% CI=−3.70, −0.97), respectively, in TM groups compared with control groups. Results from subgroup analysis suggested that TM had a greater effect on systolic BP among older participants, those with higher initial BP levels, and women, respectively. In terms of diastolic BP, it appears that TM might be more efficient in a short-term intervention and with individuals experiencing higher BP levels. However, some biases may have influenced the results, primarily a lack of information about study design and methods of BP measurement in primary studies.

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References

  1. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014; 311: 507–520.

    Article  CAS  Google Scholar 

  2. Denton KM, Hilliard LM, Tare M . Sex-related differences in hypertension: seek and ye shall find. Hypertension 2013; 62: 674–677.

    Article  CAS  Google Scholar 

  3. Lin LP, Liu CT, Liou SW, Hsu SW, Lin JD . High blood pressure in adults with disabilities: influence of gender, body weight and health behaviors. Res Dev Disabil 2012; 33: 1508–1515.

    Article  Google Scholar 

  4. Yoon SS, Ostchega Y, Louis T . Recent Trends in the Prevalence of High Blood Pressure and its Treatment and Control, 1999–2008. Centers for Disease Control and Prevention: Atlanta, GA, USA, 2010.

    Book  Google Scholar 

  5. Fan LB, Blumenthal JA, Hinderliter AL, Sherwood A . The effect of job strain on nighttime blood pressure dipping among men and women with high blood pressure. Scand J Work Environ Health 2013; 39: 112–119.

    Article  Google Scholar 

  6. Venkat Narayan KM, Ali MK, Koplan JP . Global noncommunicable diseases—where worlds meet. N Engl J Med 2010; 363: 1196–1198.

    Article  Google Scholar 

  7. Lawes CMM, Vander Hoorn S, Rodgers A . Global burden of blood-pressure-related disease, 2001. Lancet 2008; 371: 1513–1518.

    Article  Google Scholar 

  8. Egan BM, Li J, Hutchison FN, Ferdinand KC . Hypertension in the United States, 1999 to 2012: progress toward Healthy People 2020 goals. Circulation 2014; 130: 1692–1699.

    Article  Google Scholar 

  9. McDowell SE, Thomas SK, Coleman JJ, Aronson JK, Ferner RE . A practical guide to monitoring for adverse drug reactions during antihypertensive drug therapy. J R Soc Med 2013; 106: 87–95.

    Article  Google Scholar 

  10. Brook RD, Appel LJ, Rubenfire M, Ogedegbe G, Bisognano JD, Elliott WJ et al. Beyond medications and diet: alternative approaches to lowering blood pressure. Hypertension 2013; 61: 1360–1383.

    Article  CAS  Google Scholar 

  11. Chung SC, Brooks MM, Rai M, Balk JL, Rai S . Effect of Sahaja yoga meditation on quality of life, anxiety, and blood pressure control. J Altern Complement Med 2012; 18: 589–596.

    Article  Google Scholar 

  12. Gregoski MJ, Barnes VA, Tingen MS, Harshfield GA, Treiber FA . Breathing awareness meditation and LifeSkills Training programs influence upon ambulatory blood pressure and sodium excretion among African American adolescents. J Adolesc Health 2011; 48: 59–64.

    Article  Google Scholar 

  13. Campbell TS, Labelle LE, Bacon SL, Faris P, Carlson LE . Impact of mindfulness-based stress reduction (MBSR) on attention, rumination and resting blood pressure in women with cancer: a waitlist-controlled study. J Behav Med 2012; 35: 262–271.

    Article  Google Scholar 

  14. Mills WW, Farrow JT . The transcendental meditation technique and acute experimental pain. Psychosom Med 1981; 43: 157–164.

    Article  CAS  Google Scholar 

  15. Alexander CN, Langer EJ, Newman RI, Chandler HM, Davies JL . Transcendental meditation, mindfulness, and longevity: an experimental study with the elderly. J Pers Soc Psychol 1989; 57: 950–964.

    Article  CAS  Google Scholar 

  16. Schneider RH, Staggers F, Alexander CN, Sheppard W, Rainforth M, Kondwani K et al. A randomized controlled trial of stress reduction for hypertension in older African Americans. Hypertension 1995; 26: 820–827.

    Article  CAS  Google Scholar 

  17. Alexander CN, Schneider RH, Staggers F, Sheppard W, Clayborne BM, Rainforth M et al. Trial of stress reduction for hypertension in older African Americans: II. sex and risk subgroup analysis. Hypertension 1996; 28: 228–237.

    Article  CAS  Google Scholar 

  18. Barnes VA, Treiber FA, Johnson MH . Impact of transcendental meditation on ambulatory blood pressure in African-American adolescents. Am J Hypertens 2004; 17: 366–369.

    Article  Google Scholar 

  19. Paul-Labrador M, Polk D, Dwyer JH, Velasquez I, Nidich S, Rainforth M et al. Effects of a randomized controlled trial of transcendental meditation on components of the metabolic syndrome in subjects with coronary heart disease. Arch Intern Med 2006; 166: 1218–1224.

    Article  Google Scholar 

  20. Barnes VA, Kapuku GK, Treiber FA . Impact of transcendental meditation on left ventricular mass in African American adolescents. Evid Based Complement Altern Med 2012; 2012: 923153.

    Article  Google Scholar 

  21. Schneider RH, Grim CE, Rainforth MV, Kotchen T, Nidich SI, Gaylord-King C et al. Stress reduction in the secondary prevention of cardiovascular disease: randomized, controlled trial of transcendental meditation and health education in Blacks. Circ Cardiovasc Qual Outcomes 2012; 5: 750–758.

    Article  Google Scholar 

  22. Schneider RH, Alexander CN, Staggers F, Rainforth M, Salerno JW, Hartz A et al. Long-term effects of stress reduction on mortality in persons≥55 years of age with systemic hypertension. Am J Cardiol 2005; 95: 1060–1064.

    Article  Google Scholar 

  23. Anderson JW, Liu C, Kryscio RJ . Blood pressure response to transcendental meditation: a meta-analysis. Am J Hypertens 2008; 21: 310–316.

    Article  Google Scholar 

  24. Wenneberg SR, Schneider RH, Walton KG, Maclean CR, Levitsky DK, Salerno JW et al. A controlled study of the effects of the transcendental meditation program on cardiovascular reactivity and ambulatory blood pressure. Int J Neurosci 1997; 89: 15–28.

    Article  CAS  Google Scholar 

  25. Castillo-Richmond A, Schneider RH, Alexander CN, Cook R, Myers H, Nidich S et al. Effects of stress reduction on carotid atherosclerosis in hypertensive African Americans. Stroke 2000; 31: 568–573.

    Article  CAS  Google Scholar 

  26. Barnes VA, Treiber FA, Davis H . Impact of transcendental meditation on cardiovascular function at rest and during acute stress in adolescents with high normal blood pressure. J Psychosomat Res 2001; 51: 597–605.

    Article  CAS  Google Scholar 

  27. Schneider RH, Alexander CN, Staggers F, Orme-Johnson DW, Rainforth M, Salerno JW et al. A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year. Am J Hypertens 2005; 18: 88–98.

    Article  Google Scholar 

  28. Nidich SI, Rainforth MV, Haaga DAF, Hagelin J, Salerno JW, Travis F et al. A randomized controlled trial on effects of the transcendental meditation program on blood pressure, psychological distress, and coping in young adults. Am J Hypertens 2009; 22: 1326–1331.

    Article  Google Scholar 

  29. Canter PH, Ernst E . Insufficient evidence to conclude whether or not transcendental meditation decreases blood pressure: results of a systematic review of randomized clinical trials. J Hypertens 2004; 22: 2049–2054.

    Article  CAS  Google Scholar 

  30. Higgins JPT, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 2011; 343: d5928.

    Article  Google Scholar 

  31. 1999 World Health Organization-International Society of Hypertension guidelines for the management of hypertension. J Hypertens 1999; 17: 151–183.

  32. Walton KG, Schneider RH, Nidich S . Review of controlled research on the transcendental meditation program and cardiovascular disease: risk factors, morbidity, mortality. Cardiol Rev 2004; 12: 262–266.

    Article  Google Scholar 

  33. Parati G, Steptoe A . Stress reduction and blood pressure control in hypertension: a role for transcendental meditation? J Hypertens 2004; 22: 2057–2060.

    Article  CAS  Google Scholar 

  34. Goldstein CM, Josephson R, Xie S, Hughes JW . Current perspectives on the use of meditation to reduce blood pressure. Int J Hypertens 2012; 2012: 578397.

    Article  Google Scholar 

  35. Byrne MM, Thompson P . Collective equipoise, disappointment, and the therapeutic misconception: on the consequences of selection for clinical research. Med Decis Making 2006; 26: 467–479.

    Article  Google Scholar 

  36. Schulz KF, Altman DG, Moher D, CONSORT Group. CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMC Med 2010; 8: 18.

    Article  Google Scholar 

  37. Floras JS . Blood pressure variability: a novel and important risk factor. Can J Cardiol 2013; 29: 557–563.

    Article  Google Scholar 

  38. Pickering TG, Shimbo D, Haas D . Ambulatory blood-pressure monitoring. N Engl J Med 2006; 354: 2368–2374.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by funding from the National Natural Science Foundation of China (Young Research Funding-81301177, Grant 81303147). There are no conflicts of interest to declare.

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Zhenggang Bai and Jianbo Chang contributed equally.

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Correspondence to I Chi.

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Bai, Z., Chang, J., Chen, C. et al. Investigating the effect of transcendental meditation on blood pressure: a systematic review and meta-analysis. J Hum Hypertens 29, 653–662 (2015). https://doi.org/10.1038/jhh.2015.6

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