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Comparison of two generalized transfer functions for measuring central systolic blood pressure by an oscillometric blood pressure monitor

Journal of Human Hypertension volume 27, pages 204–210 (2013)Cite this article

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Abstract

Central aortic systolic blood pressure (SBP-C) can be estimated from a cuff oscillometric waveform derived during the pulse volume plethysmography (PVP) by applying a device-specific aortic pressure-to-PVP waveform-generalized transfer function (A2PGTF). The present study compared the performance of an aortic-to-brachial pressure waveforms generalized transfer function (A2BGTF), which is independent of any PVP devices, with an A2PGTF. Generalized transfer function of aortic-to-brachial (A2BGTF) and aortic-to-PVP (A2PGTF) were generated from the simultaneously obtained central aortic and brachial pressure waveforms recorded by a high-fidelity dual pressure sensor catheter, and the PVP waveform recorded by a customized noninvasive blood pressure monitor during cardiac catheterization in 40 patients, and were then applied in another 100 patients with simultaneously recorded invasive aortic pressure and noninvasively calibrated (using cuff SBP and diastolic blood pressures) PVP waveforms. The mean difference±s.d. between the noninvasively estimated and invasively recorded SBP-C was −2.1±7.7 mm Hg for A2BGTF, which was not greater than that of −3.0±7.7 mm Hg for A2PGTF (P<0.01). In conclusion, SBP-C can be measured reliably using a noninvasive blood pressure monitor by applying either an A2PGTF or A2BGTF to a noninvasively calibrated PVP waveform. The performance of an A2BGTF is not inferior to that of an A2PGTF.

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Acknowledgements

This work was supported in part by the National Science Council (NSC 96-2314-B-010-035-MY3, NSC 99-2314-B-010-034-MY3), Ministry of Education, Aim for the Top University Plan (96A-D-D131) and a research grant from an Industry-Academia Cooperation between Microlife Co., Ltd, and National Yang-Ming University.

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Author notes

  1. H-M Cheng: co-first author.

Authors and Affiliations

  1. Department of Biomedical Engineering, Chung Yuan Christian University, Chung-Li, Taiwan

    Y-T Shih & W-C Hu

  2. Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan

    H-M Cheng & C-H Chen

  3. Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    S-H Sung

  4. Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan

    H-M Cheng, S-H Sung & C-H Chen

  5. Department of Medicine, National Yang-Ming University, Taipei, Taiwan

    H-M Cheng & C-H Chen

  6. Department of Public Health, National Yang-Ming University, Taipei, Taiwan

    S-H Sung & C-H Chen

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  1. Y-T Shih
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Correspondence to W-C Hu or C-H Chen.

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Competing interests

Microlife Co., Ltd and National Yang-Ming University have signed a contract for transfer of the noninvasive central blood pressure technique.

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Supplementary Information accompanies the paper on the Journal of Human Hypertension website

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Shih, YT., Cheng, HM., Sung, SH. et al. Comparison of two generalized transfer functions for measuring central systolic blood pressure by an oscillometric blood pressure monitor. J Hum Hypertens 27, 204–210 (2013). https://doi.org/10.1038/jhh.2012.17

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