Abstract.
The MSH6 gene is one of the DNA mismatch repair genes involved in development of inherited cancers, predominantly of the colorectum and endometrium. Herein we describe the first Polish MSH6 family and the pathological and clinical data about the ovarian cancer diagnosed in the proband. Our results and reports by others indicate that, besides colorectal and endometrial cancer, the late-onset endometrioid type of ovarian cancer can be a feature of families with MSH6 germline mutations.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Additional information
Received: June 10, 2002 / Accepted: June 27, 2002
Rights and permissions
About this article
Cite this article
Suchy, J., Kurzawski, G., Jakubowska, A. et al. Ovarian cancer of endometrioid type as part of the MSH6 gene mutation phenotype. J Hum Genet 47, 529–531 (2002). https://doi.org/10.1007/s100380200079
Published:
Issue Date:
DOI: https://doi.org/10.1007/s100380200079
This article is cited by
-
Features of trinucleotide repeat instability in vivo
Cell Research (2008)