Abstract
Two newly developed microsatellite markers on Yp11 (DXYS265) and Yq11.21 (DXYS266) and our previously reported marker, on Yp11 (DXYS241), were typed by triplex polymerase chain reaction (PCR) in 102 Japanese, 18 white American, and 17 black American males. The DXYS265 locus revealed three alleles, the DXYS266 locus showed two alleles, while the DXYS241 locus showed five alleles. Nine different compound haplotypes were observed among the males. Of these, two haplotypes were common to all groups, while four were limited to Japanese. Pedigree analysis of 61 Japanese families revealed no mutations of these loci. The triplex PCR developed in this study, as well as the new loci, are useful for tracing paternal lineages in human migration studies and population analysis, in addition to Y chromosome evolutionary studies.
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Received: September 4, 2000 / Accepted: November 16, 2000
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Lee, J., Kotliarova, S., Ewis, A. et al. Y chromosome compound haplotypes with the microsatellite markers DXYS265, DXYS266, and DXYS241. J Hum Genet 46, 80–84 (2001). https://doi.org/10.1007/s100380170113
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DOI: https://doi.org/10.1007/s100380170113