Abstract
Axin and Cdx-2 play important roles in the tumorigenesis of human liver and colon. We have identified seven novel single-nucleotide polymorphisms (SNPs) in the AXIN1 gene and three in the CDX-2 gene. The identification of SNPs in these cancer-associated genes establishes a basis for future investigations to detect losses of heterozygosity in tumors; these SNPs may also provide genetic background information associated with cancer risk.
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Received: April 10, 2000 / Accepted: April 27, 2000
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Lin, YM., Kato, T., Satoh, S. et al. Identification of novel polymorphisms in the AXIN1 and CDX-2 genes. J Hum Genet 45, 254–256 (2000). https://doi.org/10.1007/s100380070036
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DOI: https://doi.org/10.1007/s100380070036
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