Summary
We have made a regional assignment of the type II collagen gene (COL2A1) on human chromosome 12 by means of anin situ hybridization technique with a biotinylated DNA probe. The precise localization of the signal was mapped to the band 12q13.1-q13.2. This result was in agreement with the previous mapping by isotopicin situ hybridization technique (12q13.1-q13.2), but not with the result of Southern hybridization analysis using somatic cell hybrids (12q14.3).
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Takahashi, Ei., Hori, Ta., Lawrence, J.B. et al. Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 byin situ hybridization with biotinylated DNA probe. Jap J Human Genet 34, 307–311 (1989). https://doi.org/10.1007/BF01929213
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DOI: https://doi.org/10.1007/BF01929213
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