Early onset of menstruation in a 45,X girl


A girl with short stature developed breasts at age 10 and began menarche at 10.3 years. When examined by us at age 15 years, she had had regular menstrual cycles. Chromosome analyses using PHA- and EB virus-stimulated lymphocytes and cultured skin fibroblasts from both elbows all revealed an exclusively 45,X karyotype. Both buccal smears and hair root cells were negative for the X-chromatin.


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Murano, I., Matsuo, K. & Kajii, T. Early onset of menstruation in a 45,X girl. Jap J Human Genet 30, 35–40 (1985). https://doi.org/10.1007/BF01883672

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  • Turner Syndrome
  • Tanner Stage
  • Regular Menstrual Cycle
  • Culture Skin Fibroblast
  • Turner Syndrome Patient