Summary
The distribution of Gc subtypes in a sample from 310 unrelated healthy Japanese living in Tokyo was examined by a slab polyacrylamide gel isoelectrofocusing followed by immunofixation. At least 9 phenotypes were distinguished which can be ascribed to four alleles:Gc 1F,Gc 1S,Gc 2 andGc J. The allele frequencies were 0.4656, 0.2590, 0.2574 and 0.0180, respectively. It was confirmed thatGc J has a polymorphic frequency in Japanese. Furthermore, two unusual phenotypes were encountered, one with a variant Gc 1 and the other with a variant Gc 2 protein, indicating the occurrence in Japanese of two further Gc alleles.
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Omoto, K., Miyake, K. The distribution of the group-specific component (Gc) subtypes in Japanese. Jap J Human Genet 23, 119–125 (1978). https://doi.org/10.1007/BF02001792
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DOI: https://doi.org/10.1007/BF02001792
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