Table 1 Concentration of cabanillasin that inhibits 50, 80 and 100% of the growth of different yeast ans filamentous fungal species after 24 and 48 h or 48 and 72 h of incubation

From: Cabanillasin, a new antifungal metabolite, produced by entomopathogenic Xenorhabdus cabanillasii JM26

  Cabanillasin 24 h Amb 24 h Cabanillasin 48 h Amb 48 h
Fungal species IC 50 IC 80 IC 100 IC 100 IC 50 IC 80 IC 100 IC 100
Candida albicans ATCC 90029 0.78 50 0.25 0.25
C. glabrata ATCC 90030 6.25 0.13 50 0.25
C. krusei ATCC 6258 6.25 6.25 25 0.13 12.5 12.5 50 0.25
C. lusitaniae CBS 6936 1.56 3.12 12.5 0.13 3.12 6.25 25 0.25
C. neoformans 12.5 0.25 0.5
  Cabanillasin 48 h Amb 48 h Cabanillasin 72 h Amb 72 h     
Fungal species IC 50 IC 80 IC 100 IC 100 IC 50 IC 80 IC 100 IC 100
A. fumigatus 50 0.25 0.5
R. oryzae 2 4
F. oxysporum 6.25 50 0.5 6.25 50 1
  1. Abbreviations: Amb, amphothericin B; ‘−’, not measurable.
  2. Concentration of molecule in μg ml−1 that inhibits 50% (IC50), 80% (IC80) or 100% (IC100) of the growth of the fungal strain when compared with the growth without inhibitor.
  3. Amphothericin B was used as a positive control.