Abstract
In our continued screening on bioactive constituents from marine-derived fungi, two novel compounds containing a rare spiral-lactone skeleton were isolated from lyophilized culture broth of the marine-derived fungus Penicillium sp. The structures of penisporolides A and B were elucidated on the basis of extensive 1D and 2D NMR as well as HRESI-MS spectroscopic data analysis. The relative stereochemistries of the compounds were assessed by analysis of NOESY data together with the comparison with data from previous literatures.
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Li, X., Sattler, I. & Lin, W. Penisporolides A and B, Two New Spiral Lactones from the Marine-derived Fungus Penicillium sp.. J Antibiot 60, 191–195 (2007). https://doi.org/10.1038/ja.2007.21
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DOI: https://doi.org/10.1038/ja.2007.21