Abstract
Two new 6-alkylsalicylic acids, salaceyins A and B were isolated by bioassay-guided fractionation from the culture of the endophytic Streptomyces laceyi MS53 and their structures were determined on the basis of spectroscopic data. Salaceyins A and B exhibited modest cytotoxicity against a human breast cancer cell line (SKBR3) with IC50 values of 3.0 and 5.5 μg/ml, respectively.
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Kim, N., Shin, J., Kim, W. et al. Cytotoxic 6-Alkylsalicylic Acids from the Endophytic Streptomyces laceyi. J Antibiot 59, 797–800 (2006). https://doi.org/10.1038/ja.2006.105
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DOI: https://doi.org/10.1038/ja.2006.105
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