Abstract
The structures of citridones A, B, B′ and C, new potentiators of miconazole activity against Candida albicans produced by Penicillium sp. FKI-1938, were elucidated by various spectroscopic analyses including UV, NMR, and MS and degradation experiments. Although citridones B and B′ were isolated as a mixture, each structure was also elucidated, indicating that they exist in equilibrium of hemiacetal epimerization. Citridones A, B and B′ have a similar phenylfuropyridone moiety.
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Fukuda, T., Tomoda, H. & Ōmura, S. Citridones, New Potentiators of Antifungal Miconazole Activity, Produced by Penicillium sp. FKI-1938. J Antibiot 58, 315–321 (2005). https://doi.org/10.1038/ja.2005.39
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DOI: https://doi.org/10.1038/ja.2005.39
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