Figure 6

From: Cooperation and cheating in Pseudomonas aeruginosa: the roles of the las, rhl and pqs quorum-sensing systems

Figure 6

Frequency-dependent relative fitness of signal-blind strains. Relative fitness of (a) the lasR mutant, (b) the pqsR mutant and (c and d) the rhlR mutant calculated as the comparison of initial and final mutant frequencies (v, left panels) or as the ratio of mutant and wild-type Malthusian growth parameters (w, right panels). Data in the left panels ac are on a double logarithmic scale and are fitted with either a power regression line (panels a and c) or an exponential regression line (panel b). Data in the right panels ac are on a semi-logarithmic scale and are fitted with either a logarithmic regression line (panels a and c) or an exponential regression line (panel b). Panel d includes initial rhlR mutant frequencies of 90 and 99% (in addition to 1, 10 and 50%) plotted on either a semi-logarithmic scale (left) or a linear scale (right), resulting in a unimodal regression. Goodness of fit is indicated by R2. Fitness trends were considered significant by one-way ANOVA (using log-transformed values for v); P-values are indicated. Assays were performed in quadruplicate.