WHO/Influenza (Seasonal). WHO 2016. http://www.who.int/mediacentre/factsheets/fs211/en/ (accessed November 10 2016).
Patterson KD, Pyle GF. The geography and mortality of the 1918 influenza pandemic. Bull Hist Med 1991; 65: 4–21.
Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003; 289: 179–186.
Izurieta HS, Thompson WW, Kramarz P, Shay DK, Davis RL, DeStefano F et al. Influenza and the rates of hospitalization for respiratory disease among infants and young children. N Engl J Med 2000; 342: 232–239.
Valdez R, Narayan KM, Geiss LS, Engelgau MM. Impact of diabetes mellitus on mortality associated with pneumonia and influenza among non-Hispanic black and white US adults. Am J Public Health 1999; 89: 1715–1721.
Sandoval C, Walter SD, Krueger P, Smieja M, Smith A, Yusuf S et al. Risk of hospitalization during influenza season among a cohort of patients with congestive heart failure. Epidemiol Infect 2007; 135: 574–582.
Neuzil KM, Reed GW, Mitchel EF, Simonsen L, Griffin MR. Impact of influenza on acute cardiopulmonary hospitalizations in pregnant women. Am J Epidemiol 1998; 148: 1094–1102.
Louie JK, Acosta M, Winter K, Jean C, Gavali S, Schechter R et al. Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California. JAMA 2009; 302: 1896–1902.
Mertz D, Kim TH, Johnstone J, Lam PP, Science M, Kuster SP et al. Populations at risk for severe or uncomplicated influenza illness: systematic review and meta-analysis. BMJ 2013; 347: f5061.
Liu B, Havers F, Chen E, Yuan Z, Yuan H, Ou J et al. Risk factors for influenza A(H7N9) disease-China, 2013. Clin Infect Dis 2014; 59: 787–794.
Centers for Disease Control and Prevention. Adult Obesity Facts. https://www.cdc.gov/obesity/data/adult.html (accessed November 10 2016).
World Health Organization. Adult Obesity Facts. http://www.who.int/mediacentre/factsheets/fs311/en/ (accessed November 10 2016).
Sridhar S, Brokstad KA, Cox RJ. Influenza vaccination strategies: comparing inactivated and live attenuated influenza vaccines. Vaccines (Basel) 2015; 3: 373–389.
Trombetta CM, Montomoli E. Influenza immunology evaluation and correlates of protection: a focus on vaccines. Expert Rev Vaccines 2016; 15: 967–976.
Coudeville L, Bailleux F, Riche B, Megas F, Andre P, Ecochard R. Relationship between haemagglutination-inhibiting antibody titres and clinical protection against influenza: development and application of a Bayesian random-effects model. BMC Med Res Methodol 2010; 10: 18.
Black S, Nicolay U, Vesikari T, Knuf M, Del Giudice G, Della Cioppa G et al. Hemagglutination inhibition antibody titers as a correlate of protection for inactivated influenza vaccines in children. Pediatr Infect Dis J 2011; 30: 1081–1085.
Centers for Disease Control and Prevention. Overview of Influenza Surveillance in the United States. http://www.cdc.gov/flu/weekly/overview.htm (accessed 10 November 2016).
Webster R, Cox N, Stohr K. World Health Organization Manual on Animal Influenza Diagnosis and Surveillance. WHO: Geneva, 2002.
Karlsson EA, Meliopoulos VA, Savage C, Livingston B, Mehle A, Schultz-Cherry S. Visualizing real-time influenza virus infection, transmission and protection in ferrets. Nat Commun 2015; 6: 6378.
R Core TeamR: A Language and Environment for Statistical Computing 2016. R Foundation for Statistical Computing: Vienna, Austria. https://www.R-project.org/.
Flegal KM, Kruszon-Moran D, Carroll MD, Fryar CD, Ogden CL. Trends in obesity among adults in the United States, 2005-2014. JAMA 2016; 315: 2284–2291.
Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003; 289: 76–79.
Xie H, Wan XF, Ye Z, Plant EP, Zhao Y, Xu Y et al. H3N2 mismatch of 2014-15 northern hemisphere influenza vaccines and head-to-head comparison between human and ferret antisera derived antigenic maps. Sci Rep 2015; 5: 15279.
Fan W, Chen XF, Shen C, Guo ZR, Dong C. Hepatitis B vaccine response in obesity: a meta-analysis. Vaccine 2016; 34: 4835–4841.
Eliakim A, Schwindt C, Zaldivar F, Casali P, Cooper DM. Reduced tetanus antibody titers in overweight children. Autoimmunity 2006; 39: 137–141.
Painter SD, Ovsyannikova IG, Poland GA. The weight of obesity on the human immune response to vaccination. Vaccine 2015; 33: 4422–4429.
Paich HA, Sheridan PA, Handy J, Karlsson EA, Schultz-Cherry S, Hudgens MG et al. Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 influenza A virus. Obesity 2013; 21: 2377–2386.
Sheridan PA, Paich HA, Handy J, Karlsson EA, Hudgens MG, Sammon AB et al. Obesity is associated with impaired immune response to influenza vaccination in humans. Int J Obes (Lond) 2012; 36: 1072–1077.
McElhaney JE, Xie D, Hager WD, Barry MB, Wang Y, Kleppinger A et al. T cell responses are better correlates of vaccine protection in the elderly. J Immunol 2006; 176: 6333–6339.
Cheng LW, Huang SW, Huang LM, Chang LY, Shao PL, Kiang D et al. Comparison of neutralizing and hemagglutination-inhibiting antibody responses for evaluating the seasonal influenza vaccine. J Virol Methods 2012; 182: 43–49.
Murphy R, Fragaszy EB, Hayward AC, Warren-Gash C. Investigating obesity as a risk factor for influenza-like illness during the 2009 H1N1 influenza pandemic using the Health Survey for England. Influenza Other Respir Viruses 2017; 11: 66–73.
Karlsson EA, Hertz T, Johnson C, Mehle A, Krammer F, Schultz-Cherry S. Obesity outweighs protection conferred by adjuvanted influenza vaccination. MBio 2016; 7: e01144–16.
Smit MA, Wang HL, Kim E, Barragan N, Aldrovandi GM, El Amin AN et al. Influenza vaccine is protective against laboratory-confirmed influenza in obese children. Ped Infect Dis J 2016; 35: 440–445.
Callahan ST, Wolff M, Hill HR, Edwards KM, . NIAID Vaccine and Treatment Evaluation Unit (VTEU) Pandemic H1N1 Vaccine Study Group. Impact of body mass index on immunogenicity of pandemic H1N1 vaccine in children and adults. J Infect Dis 2014; 210: 1270–1274.
Esposito S, Giavoli C, Trombetta C, Bianchini S, Montinaro V, Spada A et al. Immunogenicity, safety and tolerability of inactivated trivalent influenza vaccine in overweight and obese children. Vaccine 2016; 34: 56–60.
Talbot H, Coleman L, Crimin K, Zhu Y, Rock MT, Meece J et al. Association between obesity and vulnerability and serologic response to influenza vaccination in older adults. Vaccine 2012; 30: 3937–3943.
Klein SL, Hodgson A, Robinson DP. Mechanisms of sex disparities in influenza pathogenesis. J Leukocyte Biol 2012; 92: 67–73.