Table 4 GRS-stratified association of phenotype change from baseline to year 1 with exercise

From: High genetic risk individuals benefit less from resistance exercise intervention

  Exercise
  1st Tertile GRS 2nd Tertile GRS 3rd Tertile GRS
  Coeff s.e. P Coeff s.e. P Coeff s.e. P
Change weight (kg) −1.29 0.75 0.09 −0.65 0.73 0.38 1.16 0.80 0.16
Change total body fat −2121.86 656.55 0.002 −909.51 614.74 0.15 496.85 783.79 0.53
Change total body % fat −2.74 0.72 <0.001 −1.17 0.58 0.049 −0.03 0.76 0.97
Change lean soft tissue 0.99 0.27 <0.001 0.51 0.33 0.13 1.01 0.37 0.01
Change % lean soft tissue 2.80 0.71 <0.001 1.35 0.63 0.037 0.42 0.73 0.57
Change abdominal fat −0.46 0.20 0.024 −0.16 0.16 0.33 0.14 0.14 0.33
  1. Model: Change body composition=β0+β1*Exercise+error.
  2. P-values<0.05 are shown in bold.