Figure 5 | International Journal of Obesity

Figure 5

From: 4β-Hydroxywithanolide E isolated from Physalis pruinosa calyx decreases inflammatory responses by inhibiting the NF-κB signaling in diabetic mouse adipose tissue

Figure 5

The effect of the oral administration of 4βHWE (10 or 30 mg kg−1 body weight per day) for 3 weeks on glucose availability (a), area under the curve (AUC) of glucose concentration (b) in db/db mice. The effect of oral administration of 4βHWE for 4 weeks on basal plasma glucose concentration (c), and plasma insulin concentration (d) in db/db mice. The values are presented as the mean±s.e.m. of 8–10 individual determinations. In panel a, * represents P<0.05, which indicates significant decreases relative to vehicle-treated db/db mice, as identified through a two-way ANOVA with Bonferroni’s test. In panels b and c, * represents P<0.05 and *** represents P<0.001; the asterisks indicate statistically significant decreases relative to vehicle-treated db/db mice, as identified through a one-way ANOVA with Bonferroni’s test.

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