Abstract
OBJECTIVE:
To investigate the associations of anxiety and depression symptoms with weight change and incident obesity in men and women.
DESIGN:
We conducted a prospective cohort study using the Norwegian Nord-Trøndelag Health Study (HUNT).
SUBJECTS:
The study cohort included 25 180 men and women, 19–55 years of age from the second survey of the HUNT (1995–1997).
MEASUREMENTS:
Anxiety and depression symptoms were measured using the Hospital Anxiety and Depression Scale. Weight change was determined for the study period of an average 11 years. Incident obesity was new-onset obesity classified as having a body mass index of ⩾30.0 kg m2 at follow-up. The associations of anxiety or depression with weight change in kilograms (kg) was estimated using linear regression models. Risk ratios (RRs) for incident obesity associated with anxiety or depression were estimated using log-binomial regression.
RESULTS:
In men, any anxiety or depression was associated with an average 0.81 kg (95% confidence interval (CI) 0.27–1.34) larger weight change after 11 years compared with those without such symptoms (mean weight change: 5.04 versus 4.24 kg). Women with any anxiety or depression had an average 0.98 kg (95% confidence interval (CI) 0.49–1.47) larger weight change compared with those without such symptoms (mean weight change: 5.02 versus 4.04 kg). Participants with any anxiety or depression had a significantly elevated cumulative incidence of obesity (men: RR 1.37, 95% CI 1.13–1.65; women: RR 1.18, 95% CI 1.00–1.40).
CONCLUSION:
We found that symptoms of anxiety and depression were associated with larger weight change and an increased cumulative incidence of obesity in both men and women.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Association of weight change with cerebrospinal fluid biomarkers and amyloid positron emission tomography in preclinical Alzheimer’s disease
Alzheimer's Research & Therapy Open Access 17 February 2021
-
Psychiatric morbidities of female obesity before and after dieting: an Egyptian sample
Middle East Current Psychiatry Open Access 06 November 2020
-
Association between depression, anxiety and weight change in young adults
BMC Psychiatry Open Access 16 December 2019
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout

References
WHO. Strategy for Europe on Nutrition, Overweight and Obesity Related Health Issues. World Health Organization: Geneva, 2010.
Ulset E, Undheim R, Malterud K . [Has the obesity epidemic reached Norway]. Tidsskr Nor Laegeforen 2007; 127: 34–37.
Hu FB . Obesity Epidemiology. Oxford University Press: Oxford, New York, 2008.
Wittchen HU, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jonsson B et al. The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 2011; 21: 655–679.
Mykletun A, Knudsen AK, Mathiesen KS . Rapport: Psykiske lidelser i Norge: Et folkehelseperspektiv. Folkehelseinstituttet 2009.
Bjerkeset O, Romundstad P, Evans J, Gunnell D . Association of adult body mass index and height with anxiety, depression, and suicide in the general population: the HUNT study. Am J Epidemiol 2008; 167: 193–202.
Roberts RE, Deleger S, Strawbridge WJ, Kaplan GA . Prospective association between obesity and depression: evidence from the Alameda County Study. Int J Obesity 2003; 27: 514–521.
Herva A, Laitinen J, Miettunen J, Veijola J, Karvonen JT, Laksy K et al. Obesity and depression: results from the longitudinal Northern Finland 1966 Birth Cohort Study. Int J Obes (Lond) 2006; 30: 520–527.
Faith MS, Butryn M, Wadden TA, Fabricatore A, Nguyen AM, Heymsfield SB . Evidence for prospective associations among depression and obesity in population-based studies. Obes Rev 2011; 12: e438–e453.
Luppino FS, de Wit LM, Bouvy PF, Stijnen T, Cuijpers P, Penninx BW et al. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 2010; 67: 220–229.
Torres SJ, Nowson CA . Relationship between stress, eating behavior, and obesity. Nutrition 2007; 23: 887–894.
DiPietro L, Anda RF, Williamson DF, Stunkard AJ . Depressive symptoms and weight change in a national cohort of adults. Int J Obes Relat Metab Disord 1992; 16: 745–753.
Hasler G, Pine DS, Kleinbaum DG, Gamma A, Luckenbaugh D, Ajdacic V et al. Depressive symptoms during childhood and adult obesity: the Zurich Cohort Study. Mol Psychiatry 2005; 10: 842–850.
Vogelzangs N, Kritchevsky SB, Beekman AT, Newman AB, Satterfield S, Simonsick EM et al. Depressive symptoms and change in abdominal obesity in older persons. Arch Gen Psychiatry 2008; 65: 1386–1393.
Chiriboga DE, Ma Y, Li W, Olendzki BC, Pagoto SL, Merriam PA et al. Gender differences in predictors of body weight and body weight change in healthy adults. Obesity (Silver Spring, MD) 2008; 16: 137–145.
Anderson SE, Cohen P, Naumova EN, Must A . Association of depression and anxiety disorders with weight change in a prospective community-based study of children followed up into adulthood. Arch Pediatr Adolesc Med 2006; 160: 285–291.
Bodenlos JS, Lemon SC, Schneider KL, August MA, Pagoto SL . Associations of mood and anxiety disorders with obesity: comparisons by ethnicity. J Psychosom Res 2011; 71: 319–324.
de Wit LM, Fokkema M, van Straten A, Lamers F, Cuijpers P, Penninx BW . Depressive and anxiety disorders and the association with obesity, physical, and social activities. Depress Anxiety 2010; 27: 1057–1065.
Williams LJ, Pasco JA, Henry MJ, Jacka FN, Dodd S, Nicholson GC et al. Lifetime psychiatric disorders and body composition: a population-based study. J Affect Disord 2009; 118: 173–179.
Strine TW, Mokdad AH, Dube SR, Balluz LS, Gonzalez O, Berry JT et al. The association of depression and anxiety with obesity and unhealthy behaviors among community-dwelling US adults. Gen Hosp Psychiatry 2008; 30: 127–137.
Holmen JMK, Krüger Ø, Langhammer A, Holmen TL, Bratberg GH, Vatten L et al. The Nord-Trøndelag Health Study 1995–97 (HUNT 2): objectives, contents, methods and participation. Norsk Epidemiol 2003; 13: 19–32.
NTNU. The Nørd-Trøndelag Health Study. www.ntnu.edu/hunt (accessed on: 6 June 2012).
Zigmond AS, Snaith RP . The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361–370.
Mykletun A, Stordal E, Dahl AA . Hospital Anxiety and Depression (HAD) Scale: factor structure, item analyses and internal consistency in a large population. Br J Psychiat 2001; 179: 540–544.
Snaith RP . The Hospital Anxiety and Depression Scale. Health Qual Life Outcomes 2003; 1: 29.
Bjelland I, Dahl AA, Haug TT, Neckelmann D . The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res 2002; 52: 69–77.
WHO. Waist Circumference and Waist–Hip Ratio: Report of a WHO Expert Consultation, 8–11 World Health Organization: Geneva, 2008.
McNutt LA, Wu C, Xue X, Hafner JP . Estimating the relative risk in cohort studies and clinical trials of common outcomes. Am J Epidemiol 2003; 157: 940–943.
Bardone AM, Moffitt TE, Caspi A, Dickson N, Stanton WR, Silva PA . Adult physical health outcomes of adolescent girls with conduct disorder, depression, and anxiety. J Am Acad Child Adolesc Psychiatry 1998; 37: 594–601.
Nolen-Hoeksema S . Sex differences in unipolar depression: evidence and theory. Psychol Bull 1987; 101: 259–282.
Cosco TD, Doyle F, Ward M, McGee H . Latent structure of the Hospital Anxiety and Depression Scale: a 10-year systematic review. J Psychosom Res 2012; 72: 180–184.
Brennan C, Worrall-Davies A, McMillan D, Gilbody S, House A . The Hospital Anxiety and Depression Scale: a diagnostic meta-analysis of case-finding ability. J Psychosom Res 2010; 69: 371–378.
Rivenes AC, Harvey SB, Mykletun A . The relationship between abdominal fat, obesity, and common mental disorders: results from the HUNT study. J Psychosom Res 2009; 66: 269–275.
Björntorp P . Do stress reactions cause abdominal obesity and comorbidities? Obes Rev 2001; 2: 73–86.
Acknowledgements
The HUNT Study is a collaboration between HUNT Research Center (Faculty of Medicine, Norwegian University of Science and Technology NTNU), Nord-Trøndelag County Council and the Norwegian Institute of Public Health. This study was supported by the Research Council of Norway (project no. 201895/V50) and Faculty of Medicine at NTNU. We gratefully acknowledge Professor David Gunnell of the University of Bristol for his comments on the manuscript.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Additional information
Supplementary Information accompanies the paper on International Journal of Obesity website
Rights and permissions
About this article
Cite this article
Brumpton, B., Langhammer, A., Romundstad, P. et al. The associations of anxiety and depression symptoms with weight change and incident obesity: The HUNT Study. Int J Obes 37, 1268–1274 (2013). https://doi.org/10.1038/ijo.2012.204
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/ijo.2012.204
Keywords
- anxiety
- depression
- mental health
- prospective
- weight change
This article is cited by
-
Association of weight change with cerebrospinal fluid biomarkers and amyloid positron emission tomography in preclinical Alzheimer’s disease
Alzheimer's Research & Therapy (2021)
-
Psychiatric morbidities of female obesity before and after dieting: an Egyptian sample
Middle East Current Psychiatry (2020)
-
Community-Based Prevention Programs for Disordered Eating and Obesity: Updates and Current Limitations
Current Obesity Reports (2020)
-
Psychological Distress Mediates the Prospective Association of Household Income with Body Mass Index in Adolescent Girls
Affective Science (2020)
-
Association between depression, anxiety and weight change in young adults
BMC Psychiatry (2019)