Table 2 Maximum likelihood tests comparing mean BMIa between AA, AT and TT genotypes by sex

From: Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G × E) interaction

  Men Women Men and women b
  N pairs Δ Mean P-value N pairs Δ Mean P-value N pairs Δ Mean P-value
AA vs AT 19 1.344 0.045 33 1.794 0.068 83 1.314 0.006
AT vs TT 29 0.002 0.997 63 0.982 0.068 158 0.770 0.019
AA vs TT 6 1.342 0.063 5 2.775 0.011 22 2.085 <0.001
  1. Abbreviations: BMI, body mass index; DZ, dizygotic.
  2. Corrected for age, age2, birth, age × birth, age2 × birth as well as sex for men and women combined group only.
  3. bMen and women combined group also includes DZ opposite sex (DZOS) twin pairs.
  4. Means are observed across informative DZ sibpairs (N pairs=263) included in within-family association.