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Greater fat oxidation with diacylglycerol oil consumption for 14 days compared with triacylglycerol oil consumption in overweight men and women

International Journal of Obesity volume 32, pages 1841–1847 (2008)Cite this article

Abstract

Background:

Several studies have reported increased fat oxidation with diacylglycerol (DAG) oil consumption. However, the effects of long-term DAG oil consumption on energy metabolism remain to be investigated.

Objective:

The objective of this study was to compare the effects of 14 days of either DAG or triacylglycerol (TAG) oil consumption on substrate oxidation, energy expenditure (EE) and dietary fat oxidation.

Design:

Eight males and six females participated in this randomized, double-blind, crossover feeding study. Each patient consumed the 14-day controlled test diet containing either 10 g day−1 of DAG or TAG oil for acclimatization before a respiratory chamber measurement, followed by a 2-week washout period between diet treatments. Substrate oxidation and EE were measured in the respiratory chamber at the end of each dietary treatment. The patients consumed test oil as 15% of total caloric intake in the respiratory chamber (mean test oil intake was 36.1±6.6 g day−1).

Results:

Twenty-four hour fat oxidation was significantly greater with 14 days of DAG oil consumption compared with TAG oil consumption (78.6±19.6 and 72.6±14.9 g day−1, respectively, P<0.05). There were no differences in body weight or body composition between diet treatments. Dietary fat oxidation was determined using the recovery rate of 13CO2 in breath, and was significantly enhanced with DAG oil consumption compared with TAG oil consumption, measured over 22 h after ingestion of 13C-labelled triolein. Resting metabolic rate (RMR) was significantly greater with DAG oil consumption compared with TAG oil consumption (1766±337 and 1680±316 kcal day−1, respectively, P<0.05).

Conclusion:

Consumption of DAG oil for 14 days stimulates both fat oxidation and RMR compared with TAG oil consumption, which may explain the greater loss of body weight and body fat with DAG oil consumption that has been observed in weight-loss studies.

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Acknowledgements

This study was supported by Kao Corporation. We thank Hironobu Miyauchi of Fuji Medical Science Co., Ltd. for assistance with the measurement of energy metabolism in the respiratory chamber, and Dr Akiyoshi Uchiyama of Artage Inc. for advice on the statistical analysis.

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Authors and Affiliations

  1. Health Care Food Research Laboratories, Kao Corporation, Tokyo, Japan

    M Hibi, H Takase, K Yasunaga, T Yamaguchi, D Shiiba, S Saito, R Yokoyama, N Kudo, Y Katsuragi, S Meguro & I Tokimitsu

  2. Clínica Emilio Moriguchi, Tokyo, Japan

    A Shimizu

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Correspondence to M Hibi.

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Hibi, M., Takase, H., Yasunaga, K. et al. Greater fat oxidation with diacylglycerol oil consumption for 14 days compared with triacylglycerol oil consumption in overweight men and women. Int J Obes 32, 1841–1847 (2008). https://doi.org/10.1038/ijo.2008.197

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