Original Article | Published:

Erectile dysfunction in patients with plaque psoriasis: the relation of depression and cardiovascular factors

International Journal of Impotence Research volume 28, pages 96100 (2016) | Download Citation

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Abstract

Psoriasis is a chronic inflammatory skin disease and seems to be associated with erectile dysfunction (ED). ED is a predictor of future cardiovascular disease. It is important to identify ED early and investigate cardiovascular problems in psoriasis patients. The sample consisted of 191 psoriasis patients and 191 healthy men. One hundred and one of 191 (52.9%) patients with psoriasis were indicative of ED, compared with 40.3% in control group, reflecting an age-adjusted odds ratio of 1.965 in favor of the psoriasis group. A univariate analysis in the psoriasis group indicated that age, hypertension, hyperlipidemia, diabetes mellitus and depressive symptoms were the risk factors for ED. The multivariate logistic regression model indicated that increasing age, hypertension, hyperlipidemia and depressive symptoms were independent risk factors for ED in psoriasis. The more severe depressive symptoms increased the risk of ED and especially moderate–severe ED. The diagnosis of ED may help prevent emotional and physical discomfort in men and aid in identifying reversible cardiovascular risk factors. Screening of ED may become a part of routine care in the management of psoriasis patients.

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Author information

Author notes

    • S Ji
    •  & Z Zang

    These authors contributed equally to this work.

Affiliations

  1. Department of Dermatology, Guangdong Provincial Dermatology Hospital, Guangzhou, China

    • S Ji
    • , M Gu
    •  & B Yang
  2. Department of Infertility and Sexual Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    • Z Zang
  3. Department of Dermatology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    • H Ma
  4. Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

    • Y Han
  5. Department of Dermatology, Guangfo Hospital, Guangzhou Medical University, Foshan, China

    • L Wang
  6. Department of Dermatology, Guangzhou Nansha Central Hospital, Guangzhou, China

    • S Jia

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Competing interests

The authors declare no conflict of interest.

Corresponding author

Correspondence to B Yang.

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DOI

https://doi.org/10.1038/ijir.2016.6

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