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Review of non-surgical treatment options for Peyronie's Disease

International Journal of Impotence Research volume 24, pages 1–10 (2012)Cite this article

Abstract

Non-surgical treatment of Peyronie's disease (PD) has come a long way since it was first described in 1743. A myriad of treatment options are currently available, including oral, intralesional and external energy therapies. The purpose of this article is to review the contemporary literature on non-surgical therapies for PD, and where possible, focus on randomized, placebo-controlled trials, as well as review the latest guidelines for the management of PD from the International Committee on Sexual Medicine, which conveyed its findings in July 2009. At this time, it appears that a combination of oral agents and/or intralesional injection with traction therapy may provide a synergy between the chemical effects of the drugs and the mechanical effects of traction. Until a reliable treatment emerges, it does appear that some of the non-surgical treatments discussed can be used to stabilize the scarring process and may result in some reduction of deformity with improved sexual function.

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  1. Department of Urology, Rush University Medical Center, Chicago, IL, USA

    S M Larsen & L A Levine

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Laurence A Levine, Auxilium consultant, investigator, speaker; AMS consultant, speaker; Coloplast consultant, speaker; US Physiomed consultant; Pfizer consultant; Slate pharmaceutical consultant. Stephen M Larsen declare no conflict of interest.

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Larsen, S., Levine, L. Review of non-surgical treatment options for Peyronie's Disease. Int J Impot Res 24, 1–10 (2012). https://doi.org/10.1038/ijir.2011.45

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