Table 3 Association between serum bicarbonate level and all-cause mortality stratified by sex, body mass index and serum uric acid level

From: Association between the markers of metabolic acid load and higher all-cause and cardiovascular mortality in a general population with preserved renal function

Quartile of serum bicarbonate (n) 1Q (6134) 2Q (8110) 3Q (8968) 4Q (8378) P for interaction
Sex a
 Men 1.297 (0.889–1.893) 1.123 (0.775–1.625) 1.071 (0.741–1.548) Reference 0.786
 Women 1.671 (0.947–2.948) 1.085 (0.604–1.949) 1.208 (0.808–1.806) Reference  
Body mass index b
 <23 kg m2 1.184 (0.711–1.973) 1.157 (0.717–1.868) 0.908 (0.553–1.490) Reference 0.743
23 kg m2 1.601 (1.071–2.393) 1.103 (0.729–1.670) 1.208 (0.808–1.806) Reference  
Serum uric acid c
Mediand 1.210 (0.815–1.796) 0.902 (0.607–1.340) 0.877 (0.594–1.296) Reference 0.917
 >Median 2.504 (1.462–4.286) 2.045 (1.196–3.497) 1.731 (1.016–2.950) Reference  
  1. aAdjusted hazard ratio (95% confidence interval) by the Cox proportional hazard model adjusted for age, history of diabetes and/or hypertension medication, smoking, regular exercise, regular alcohol ingestion, body mass index, systolic blood pressure, fasting serum glucose, serum uric acid, serum albumin, glomerular filtration rate estimated with the Chronic Kidney Disease Epidemiology Collaboration creatinine equation, serum triglyceride, serum high-density lipoprotein-cholesterol and albuminuria.
  2. bAdjusted hazard ratio (95% confidence interval) by the Cox proportional hazard model adjusted for age, sex, history of diabetes and/or hypertension medication, smoking, regular exercise, regular alcohol ingestion, systolic blood pressure, fasting serum glucose, serum uric acid, serum albumin, glomerular filtration rate estimated with the Chronic Kidney Disease Epidemiology Collaboration creatinine equation, serum triglyceride, serum high-density lipoprotein-cholesterol and albuminuria.
  3. cAdjusted hazard ratio (95% confidence interval) by the Cox proportional hazard model adjusted for age, sex, history of diabetes and/or hypertension medication, smoking, regular exercise, regular alcohol ingestion, body mass index, systolic blood pressure, fasting serum glucose, serum albumin, glomerular filtration rate estimated with the Chronic Kidney Disease Epidemiology Collaboration creatinine equation, serum triglyceride, serum high-density lipoprotein-cholesterol and albuminuria.
  4. d5.8 mg dl−1 in men and 4.2 mg dl−1 in women.